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IGF-IR (Phospho Tyr1346) Cell-Based Colorimetric ELISA Kit

-KA1106C

Catalog: KA1106C
Size
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Status
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96well
$470.00
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Main Information
Reactivity

Human, Mouse, Rat

Applications

ELISA

Conjugate/Modification


Phospho

Detailed Information
Storage
2-8°C/6 months
Modification
Phospho
Detection Method
Colorimetric
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Antigen&Target Information
Gene Name:
IGF1R
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Other Name:
Insulin-like growth factor 1 receptor ;
Insulin-like growth factor I receptor ;
IGF-I receptor ;
CD antigen CD221 ;
[Cleaved into: Insulin-like growth factor 1 receptor alpha chain ;
Insulin-like growth factor 1 receptor beta chain]
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Database Link:
Organism Gene ID SwissProt
Human 3480; P08069;
Mouse Q60751;
Rat P24062;
Function:
cell morphogenesis, cell morphogenesis involved in differentiation, reproductive developmental process, regulation of DNA replication, protein complex assembly, protein amino acid phosphorylation, phosphorus metabolic process,phosphate metabolic process, anti-apoptosis, immune response, establishment or maintenance of cell polarity, cell surface receptor linked signal transduction, enzyme linked receptor protein signaling pathway, transmembrane receptor protein tyrosine kinase signaling pathway, intracellular signaling cascade, protein kinase cascade,axonogenesis, sex determination, positive regulation of cell proliferation, insulin receptor signaling pathway, response to endogenous stimulus, response to hormone stimulus, positive regulation of biosynthetic process, response to organic substance, positive regulation of macromolecule biosynthetic process, positive regulation of macromolecule metabolic process, regulation of cell death, phosphoinositide 3-kinase cascade, phosphorylation, second-messenger-mediated signaling, establishment of cell polarity, cell projection organization, neuron differentiation, male sex determination, regulation of cell migration, positive regulation of cell migration, mammary gland development, neuron projection development, positive regulation of cellular biosynthetic process, response to insulin stimulus, cellular response to insulin stimulus, cellular response to hormone stimulus, cellular component morphogenesis, cell part morphogenesis, regulation of locomotion, positive regulation of locomotion, regulation of cell proliferation, regulation of apoptosis, negative regulation of apoptosis, regulation of programmed cell death, negative regulation of programmed cell death, response to peptide hormone stimulus, macromolecular complex subunit organization,positive regulation of DNA replication, positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process, protein amino acid autophosphorylation, insulin-like growth factor receptor signaling pathway,phosphoinositide-mediated signaling, neuron development, cell morphogenesis involved in neuron differentiation,gland development, neuron projection morphogenesis, cell projection morphogenesis, regulation of DNA metabolic process, positive regulation of DNA metabolic process, positive regulation of nitrogen compound metabolic process,protein oligomerization, protein tetramerization, regulation of cell motion, positive regulation of cell motion, protein heterooligomerization, negative regulation of cell death, macromolecular complex assembly, protein complex biogenesis,
show all
Cellular Localization:
Cell membrane ; Single-pass type I membrane protein .
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Tissue Expression:
Found as a hybrid receptor with INSR in muscle, heart, kidney, adipose tissue, skeletal muscle, hepatoma, fibroblasts, spleen and placenta (at protein level). Expressed in a variety of tissues. Overexpressed in tumors, including melanomas, cancers of the colon, pancreas prostate and kidney.
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Signaling Pathway
Cellular Processes >> Transport and catabolism >> Autophagy - animal Cellular Processes >> Cellular community - eukaryotes >> Focal adhesion Cellular Processes >> Cellular community - eukaryotes >> Adherens junction Cellular Processes >> Cellular community - eukaryotes >> Signaling pathways regulating pluripotency of stem cells Organismal Systems >> Aging >> Longevity regulating pathway Organismal Systems >> Aging >> Longevity regulating pathway - multiple species Human Diseases >> Cancer: overview >> Pathways in cancer Human Diseases >> Cancer: overview >> Transcriptional misregulation in cancer Human Diseases >> Cancer: specific types >> Hepatocellular carcinoma Human Diseases >> Cancer: specific types >> Glioma Human Diseases >> Cancer: specific types >> Melanoma Human Diseases >> Cancer: specific types >> Prostate cancer Human Diseases >> Cancer: specific types >> Breast cancer Environmental Information Processing >> Signal transduction >> MAPK signaling pathway Environmental Information Processing >> Signal transduction >> Ras signaling pathway Environmental Information Processing >> Signal transduction >> Rap1 signaling pathway Environmental Information Processing >> Signal transduction >> HIF-1 signaling pathway Environmental Information Processing >> Signal transduction >> FoxO signaling pathway Environmental Information Processing >> Signal transduction >> PI3K-Akt signaling pathway Environmental Information Processing >> Signal transduction >> AMPK signaling pathway Environmental Information Processing >> Signal transduction >> mTOR signaling pathway
Catalog: KA1106C
Size
Price
Status
Qty.
96well
$470.00
In stock

0

Add to cart

Collected

Collect

Customized Service

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