Catalog: YP1872
Size
Price
Status
Qty.
200μL
$936.00
2 months
0
100μL
$560.00
2 months
0
50μL
$300.00
2 months
0
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Collected
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Main Information
Target
PFK-2 car Phospho Ser466
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, IHC
MW
58kD (Observed)
Conjugate/Modification
phosphate
Detailed Information
Recommended Dilution Ratio
WB 1:500-2000; IHC 1:50-200
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Specificity
This antibody detects endogenous levels of PFKFB2 (Phospho Ser466) Rabbit pAb at Human, Mouse,Rat
Purification
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Storage
-15°C to -25°C/1 year (Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
58kD
Modification
phosphate
Clonality
Polyclonal
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PFK-2 car Rabbit pAb
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PFK-2 car (Phospho Ser483) Rabbit pAb
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ELISA Kits
Total PFKFB2 Cell-Based Colorimetric ELISA Kit
KA4230C
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ELISA Kits
Total PFK-2 car Cell-Based Colorimetric ELISA Kit
KA3479C
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ELISA Kits
PFKFB2 (Phospho Ser483) Cell-Based Colorimetric ELISA Kit
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from human PFKFB2 (Phospho Ser466)
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Specificity:
This antibody detects endogenous levels of PFKFB2 (Phospho Ser466) Rabbit pAb at Human, Mouse,Rat
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Gene Name:
PFKFB2
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Protein Name:
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 (6PF-2-K/Fru-2,6-P2ase 2) (PFK/FBPase 2) (6PF-2-K/Fru-2,6-P2ase heart-type isozyme) [Includes: 6-phosphofructo-2-kinase (EC 2.7.1.105) ; Fructose-2,6-bisphosphatase (EC 3.1.3.46) ]
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Other Name:
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 ;
6PF-2-K/Fru-2,6-P2ase 2 ;
PFK/FBPase 2 ;
6PF-2-K/Fru-2,6-P2ase heart-type isozyme ;
[Includes: 6-phosphofructo-2-kinase ;
Fructose-2,6-bisphosphatase ;
]
6PF-2-K/Fru-2,6-P2ase 2 ;
PFK/FBPase 2 ;
6PF-2-K/Fru-2,6-P2ase heart-type isozyme ;
[Includes: 6-phosphofructo-2-kinase ;
Fructose-2,6-bisphosphatase ;
]
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Database Link:
Background:
6-phosphofructo-2-kinase/fructose-2 ,6-biphosphatase 2 (PFKFB2) Homo sapiens The protein encoded by this gene is involved in both the synthesis and degradation of fructose-2 ,6-bisphosphate , a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2 ,6-bisphosphate , and a fructose-2 ,6-biphosphatase activity that catalyzes the degradation of fructose-2 ,6-bisphosphate. This protein regulates fructose-2 ,6-bisphosphate levels in the heart , while a related enzyme encoded by a different gene regulates fructose-2 ,6-bisphosphate levels in the liver and muscle. This enzyme functions as a homodimer. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq , Jul 2008] ,
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Function:
Catalytic activity:ATP + D-fructose 6-phosphate = ADP + beta-D-fructose 2 ,6-bisphosphate. ,Catalytic activity:Beta-D-fructose 2 ,6-bisphosphate + H (2) O = D-fructose 6-phosphate + phosphate. ,enzyme regulation:Phosphorylation results in the activation of the kinase activity. ,Function:Synthesis and degradation of fructose 2 ,6-bisphosphate. ,similarity:In the C-terminal section; belongs to the phosphoglycerate mutase family. ,subunit:Homodimer. ,tissue specificity:Heart. ,
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Tissue Expression:
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Research Areas:
>>Fructose and mannose metabolism ;
>>Metabolic pathways ;
>>AMPK signaling pathway ;
>>Thyroid hormone signaling pathway
>>Metabolic pathways ;
>>AMPK signaling pathway ;
>>Thyroid hormone signaling pathway
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Signaling Pathway
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Catalog: YP1872
Size
Price
Status
Qty.
200μL
$936.00
2 months
0
100μL
$560.00
2 months
0
50μL
$300.00
2 months
0
Add to cart
Collected
Collect
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