Catalog: KE1660
Size
Price
Status
Qty.
5*96well
$1,850.00
3 weeks
0
2*96well
$740.00
3 weeks
0
96well
$370.00
3 weeks
0
Add to cart
Collected
Collect
Main Information
Reactivity
Rat
Applications
ELISA
Conjugate/Modification
Unmodified
Detailed Information
Specificity
Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma
Storage
2-8°C/6 months
Modification
Unmodified
Sample Type
Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma
Detection Method
Colorimetric
Detection Range
31.25--2000pg/mL
Sensitivity
18.75pg/mL
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Antigen&Target Information
Specificity:
Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma
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Protein Name:
MAPτ(Microtubule Associated Protein Tau/Tau Protein)
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Cellular Localization:
Cytoplasm, cytosol . Cell membrane ; Peripheral membrane protein ; Cytoplasmic side . Cytoplasm, cytoskeleton . Cell projection, axon . Cell projection, dendrite . Secreted . Mostly found in the axons of neurons, in the cytosol and in association with plasma membrane components (PubMed:10747907). Can be secreted; the secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10; it results in protein translocation from the cytoplasm into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) followed by vesicle entry and secretion (PubMed:32272059). .
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Tissue Expression:
Expressed in neurons. Isoform PNS-tau is expressed in the peripheral nervous system while the others are expressed in the central nervous system.
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Signaling Pathway
Human Diseases >> Neurodegenerative disease >> Alzheimer disease
Human Diseases >> Neurodegenerative disease >> Parkinson disease
Human Diseases >> Neurodegenerative disease >> Pathways of neurodegeneration - multiple diseases
Environmental Information Processing >> Signal transduction >> MAPK signaling pathway
Reference Citation({{totalcount}})
Catalog: KE1660
Size
Price
Status
Qty.
5*96well
$1,850.00
3 weeks
0
2*96well
$740.00
3 weeks
0
96well
$370.00
3 weeks
0
Add to cart
Collected
Collect
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