Catalog: YP1843
Size
Price
Status
Qty.
200μL
$936.00
3 weeks
0
100μL
$560.00
3 weeks
0
50μL
$300.00
3 weeks
0
Add to cart
Collected
Collect
Main Information
Target
Caveolin-2 Phospho Ser23
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, IHC
MW
26kD (Observed)
Conjugate/Modification
phosphate
Detailed Information
Recommended Dilution Ratio
WB 1:500-2000; IHC 1:50-200
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Specificity
This antibody detects endogenous levels of Caveolin 2 (Phospho Ser23) Rabbit pAb at Human, Mouse,Rat
Purification
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Storage
-15°C to -25°C/1 year (Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
26kD
Modification
phosphate
Clonality
Polyclonal
Related Products
Secondary Antibodies
Goat Anti Mouse IgG(H+L) (HRP)
RS0001
More→
Secondary Antibodies
Goat Anti Rabbit IgG(H+L) (HRP)
RS0002
More→
Primary Antibodies
β-actin (PTR2364) Mouse mAb
YM3028
More→
Primary Antibodies
GAPDH (PTR2304) Mouse mAb
YM3029
More→
Antigen&Target Information
Immunogen:
Synthesized peptide derived from human Caveolin 2 (Phospho Ser23)
show all
Specificity:
This antibody detects endogenous levels of Caveolin 2 (Phospho Ser23) Rabbit pAb at Human, Mouse,Rat
show all
Gene Name:
CAV2
show all
Protein Name:
Caveolin-2
show all
Other Name:
CAV2 ;
Caveolin-2
Caveolin-2
show all
Database Link:
Background:
caveolin 2 (CAV2) Homo sapiens The protein encoded by this gene is a major component of the inner surface of caveolae , small invaginations of the plasma membrane , and is involved in essential cellular functions , including signal transduction , lipid metabolism , cellular growth control and apoptosis. This protein may function as a tumor suppressor. This gene and related family member (CAV1) are located next to each other on chromosome 7 , and express colocalizing proteins that form a stable hetero-oligomeric complex. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. Additional isoforms resulting from the use of alternate in-frame translation initiation codons have also been described , and shown to have preferential localization in the cell (PMID:11238462) . [provided by RefSeq , May 2011] ,
show all
Function:
Function:May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. ,Function:May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Caveolin-2 may function as an accessory protein in conjunction with caveolin-1. ,online information:Caveolin entry ,similarity:Belongs to the caveolin family. ,subcellular location:Potential hairpin-like structure in the membrane. Membrane protein of caveolae. ,subunit:Homodimer. Caveolin-1 and -2 colocalize and form a stable hetero-oligomeric complex. ,tissue specificity:Expressed in endothelial cells , smooth muscle cells , skeletal myoblasts and fibroblasts. ,
show all
Cellular Localization:
Nucleus. Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein. Membrane , caveola; Peripheral membrane protein. Potential hairpin-like structure in the membrane. Membrane protein of caveolae. Tyr-19-phosphorylated form is enriched at sites of cell-cell contact and is translocated to the nucleus in complex with MAPK1 in response to insulin (By similarity) . Tyr-27-phosphorylated form is located both in the cytoplasm and plasma membrane. CAV1-mediated Ser-23-phosphorylated form locates to the plasma membrane. Ser-36-phosphorylated form resides in intracellular compartments. .
show all
Tissue Expression:
Research Areas:
>>Endocytosis ;
>>Focal adhesion ;
>>Prion disease ;
>>Bacterial invasion of epithelial cells ;
>>Proteoglycans in cancer ;
>>Fluid shear stress and atherosclerosis
>>Focal adhesion ;
>>Prion disease ;
>>Bacterial invasion of epithelial cells ;
>>Proteoglycans in cancer ;
>>Fluid shear stress and atherosclerosis
show all
Signaling Pathway
Reference Citation({{totalcount}})
Catalog: YP1843
Size
Price
Status
Qty.
200μL
$936.00
3 weeks
0
100μL
$560.00
3 weeks
0
50μL
$300.00
3 weeks
0
Add to cart
Collected
Collect
Recently Viewed Products
Clear allPRODUCTS
CUSTOMIZED
ABOUT US
Toggle night Mode
{{pinfoXq.title || ''}}
Catalog: {{pinfoXq.catalog || ''}}
Filter：
All
{{item.name}}
{{pinfo.title}}
-{{pinfo.catalog}}
Main Information
Target
{{pinfo.target}}
Reactivity
{{pinfo.react}}
Applications
{{pinfo.applicat}}
Conjugate/Modification
{{pinfo.coupling}}/{{pinfo.modific}}
MW (kDa)
{{pinfo.mwcalc}}
Host Species
{{pinfo.hostspec}}
Isotype
{{pinfo.isotype}}
Product {{index}}/{{pcount}}
Prev
Next
{{pvTitle}}
Scroll wheel zooms the picture
{{pvDescr}}