Catalog: YP1636
Size
Price
Status
Qty.
200μL
$600.00
3 weeks
0
100μL
$340.00
3 weeks
0
50μL
$190.00
3 weeks
0
Add to cart
Collected
Collect
Main Information
Target
phosphoenolpyruvate carboxylase Phospho Ser15
Host Species
Rabbit
Reactivity
A.comosus, A.thaliana, H.vulgare, J.curcas, M.crystallinum, N.tabacum, Z.mays, T.weissfloggi
Applications
WB, IHC, ELISA
MW
105-110kD (Observed)
Conjugate/Modification
phosphate
Detailed Information
Recommended Dilution Ratio
WB 1:500-2000; IHC 1:50-300; ELISA 1:2000-20000
Formulation
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
Specificity
The antibody detects endogenous PEPC (Phospho Ser15) protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year (Do not lower than -25°C)
MW(Observed)
105-110kD
Modification
phosphate
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
Synthetic Peptide of PEPC (Phospho Ser15)
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Specificity:
The antibody detects endogenous PEPC (Phospho Ser15) protein.
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Gene Name:
PGC
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Protein Name:
Phosphoenolpyruvate carboxylase
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Other Name:
PGC ;
Gastricsin ;
Pepsinogen C
Gastricsin ;
Pepsinogen C
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Background:
This gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1. [provided by RefSeq , Oct 2009] ,
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Function:
Catalytic activity:More restricted specificity than pepsin A , but shows preferential cleavage at Tyr-|-Xaa bonds. High activity on hemoglobin. ,Function:Hydrolyzes a variety of proteins. ,similarity:Belongs to the peptidase A1 family. ,
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Cellular Localization:
Secreted.
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Tissue Expression:
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Reference Citation({{totalcount}})
Catalog: YP1636
Size
Price
Status
Qty.
200μL
$600.00
3 weeks
0
100μL
$340.00
3 weeks
0
50μL
$190.00
3 weeks
0
Add to cart
Collected
Collect
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