Human BDNF(Brain Derived Neurotrophic Factor) ELISA Kit
-KE1464
Catalog: KE1464
Size
Price
Status
Qty.
5*96well
$1,850.00
3 weeks
0
2*96well
$740.00
3 weeks
0
96well
$370.00
3 weeks
0
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Collected
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Main Information
Reactivity
Human
Applications
ELISA
Conjugate/Modification
Unmodified
Detailed Information
Specificity
Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma
Storage
2-8°C/6 months,Ship by ice bag
Modification
Unmodified
Sample Type
Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma
Detection Method
Colorimetric
Detection Range
31.25--2000pg/mL
Sensitivity
18.75pg/mL
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Antigen&Target Information
Specificity:
Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma
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Gene Name:
BDNF
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Protein Name:
BDNF(Brain Derived Neurotrophic Factor)
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Other Name:
Brain-derived neurotrophic factor ;
BDNF ;
Abrineurin ;
BDNF ;
Abrineurin ;
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Database Link:
| Organism | Gene ID | SwissProt |
|---|---|---|
| Human | P23560; |
Background:
This gene encodes a member of the nerve growth factor family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. Binding of this protein to its cognate receptor promotes neuronal survival in the adult brain. Expression of this gene is reduced in Alzheimer's, Parkinson's, and Huntington's disease patients. This gene may play a role in the regulation of the stress response and in the biology of mood disorders. [provided by RefSeq, Nov 2015]
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Function:
Important signaling molecule that activates signaling cascades downstream of NTRK2 (PubMed:11152678).
During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability
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Cellular Localization:
Secreted .; [BDNF precursor form]: Secreted . A proportion of BDNF is secreted as immature precursor (proBDNF). .
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Reference Citation({{totalcount}})
Catalog: KE1464
Size
Price
Status
Qty.
5*96well
$1,850.00
3 weeks
0
2*96well
$740.00
3 weeks
0
96well
$370.00
3 weeks
0
Add to cart
Collected
Collect
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