β-Tubulin (Acetyl Lys379) Rabbit pAb

-YK0178

Main Information
Target

Tubulin β Acetyl Lys379

Host Species

Rabbit

Reactivity

Human, Mouse, Rat

Applications

WB, ELISA

MW

50kD (Observed)

Conjugate/Modification


Acetyl

Detailed Information
Recommended Dilution Ratio
WB 1:1000-2000; ELISA 1:5000-20000
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
This antibody detects endogenous levels of Human,Mouse,Rat Tubulin β (Acetyl Lys379).The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):LFkRI
Purification
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
50kD
Modification
Acetyl
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from human Tubulin β (Acetyl Lys379)
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Specificity:
This antibody detects endogenous levels of Human,Mouse,Rat Tubulin β (Acetyl Lys379).The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):LFkRI
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Gene Name:
TUBB2A TUBB2
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Protein Name:
Tubulin β (Acetyl Lys379)
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Other Name:
Tubulin beta-2A chain
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Database Link:
Organism Gene ID SwissProt
Human 7280; Q13885;Q9BVA1;Q13509;P04350;P68371;P07437;Q9BUF5;;
Mouse 22151; Q7TMM9;
Rat 498736; P85108;
Background:
Microtubules, key participants in processes such as mitosis and intracellular transport, are composed of heterodimers of alpha- and beta-tubulins. The protein encoded by this gene is a beta-tubulin. Defects in this gene are associated with complex cortical dysplasia with other brain malformations-5. Two transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2015],
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Function:
Function:Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain.,similarity:Belongs to the tubulin family.,subunit:Dimer of alpha and beta chains.,
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Cellular Localization:
Cytoplasm, cytoskeleton .
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Research Areas:
>>Phagosome ;
>>Gap junction ;
>>Alzheimer disease ;
>>Parkinson disease ;
>>Amyotrophic lateral sclerosis ;
>>Huntington disease ;
>>Prion disease ;
>>Pathways of neurodegeneration - multiple diseases ;
>>Pathogenic Escherichia coli infection ;
>>Salmonella infection
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