Catalog: YK0161
Size
Price
Status
Qty.
200μL
$600.00
In stock
0
100μL
$340.00
In stock
0
50μL
$190.00
In stock
0
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Main Information
Target
MYH-pan Acetyl Lys1394
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, IHC
MW
77kD (Observed)
Conjugate/Modification
Acetyl
Detailed Information
Recommended Dilution Ratio
WB 1:500-2000; IHC 1:50-300
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
This antibody detects endogenous levels of Human,Mouse,Rat MYH-pan (Acetyl Lys1394).The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):EAkKK
Purification
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
77kD
Modification
Acetyl
Clonality
Polyclonal
Isotype
IgG
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β-actin (PTR2364) Mouse mAb
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from human MYH-pan (Acetyl Lys1394)
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Specificity:
This antibody detects endogenous levels of Human,Mouse,Rat MYH-pan (Acetyl Lys1394).The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):EAkKK
show all
Gene Name:
MYH1/MYH2/MYH3/PTPRJ/MYH6/MYH7/MYH8
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Protein Name:
MYH-pan (Acetyl Lys1394)
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Other Name:
Myosin-1 ;
Myosin heavy chain 1 ;
Myosin heavy chain 2x ;
MyHC-2x ;
Myosin heavy chain IIx/d ;
MyHC-IIx/d ;
Myosin heavy chain, skeletal muscle, adult 1 ;
Myosin heavy chain 1 ;
Myosin heavy chain 2x ;
MyHC-2x ;
Myosin heavy chain IIx/d ;
MyHC-IIx/d ;
Myosin heavy chain, skeletal muscle, adult 1 ;
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Database Link:
Background:
Myosin is a major contractile protein which converts chemical energy into mechanical energy through the hydrolysis of ATP. Myosin is a hexameric protein composed of a pair of myosin heavy chains (MYH) and two pairs of nonidentical light chains. Myosin heavy chains are encoded by a multigene family. In mammals at least 10 different myosin heavy chain (MYH) isoforms have been described from striated, smooth, and nonmuscle cells. These isoforms show expression that is spatially and temporally regulated during development. [provided by RefSeq, Jul 2008],
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Function:
Domain:The rodlike tail sequence is highly repetitive, showing cycles of a 28-residue repeat pattern composed of 4 heptapeptides, characteristic for alpha-helical coiled coils.,Function:Muscle contraction.,miscellaneous:Each myosin heavy chain can be split into 1 light meromyosin (LMM) and 1 heavy meromyosin (HMM). It can later be split further into 2 globular subfragments (S1) and 1 rod-shaped subfragment (S2).,similarity:Contains 1 IQ domain.,similarity:Contains 1 myosin head-like domain.,subcellular location:Thick filaments of the myofibrils.,subunit:Muscle myosin is a hexameric protein that consists of 2 heavy chain subunits (MHC), 2 alkali light chain subunits (MLC) and 2 regulatory light chain subunits (MLC-2).,
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Cellular Localization:
Cytoplasm, myofibril. Thick filaments of the myofibrils.
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Signaling Pathway
Cellular Processes >> Cellular community - eukaryotes >> Adherens junction
Organismal Systems >> Endocrine system >> Thyroid hormone signaling pathway
Organismal Systems >> Circulatory system >> Cardiac muscle contraction
Organismal Systems >> Circulatory system >> Adrenergic signaling in cardiomyocytes
Environmental Information Processing >> Signal transduction >> cGMP-PKG signaling pathway
Reference Citation({{totalcount}})
Catalog: YK0161
Size
Price
Status
Qty.
200μL
$600.00
In stock
0
100μL
$340.00
In stock
0
50μL
$190.00
In stock
0
Add to cart
Collected
Collect
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