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Human Thrombomodulin ELISA Kit

-KE1252

Catalog: KE1252
Size
Price
Status
Qty.
5*96well
$1,850.00
3 weeks

0

2*96well
$740.00
3 weeks

0

96well
$370.00
3 weeks

0

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Main Information
Reactivity

Human

Applications

ELISA

Conjugate/Modification


Unmodified

Detailed Information
Specificity
Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma
Storage
2-8°C/6 months
Modification
Unmodified
Sample Type
Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma
Detection Method
Colorimetric
Sensitivity
32-2000 pg/ml
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Antigen&Target Information
Specificity:
Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma
show all
Gene Name:
THBD
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Protein Name:
Thrombomodulin
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Other Name:
THBD ;
THRM ;
Thrombomodulin ;
TM ;
Fetomodulin ;
CD antigen CD141
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Database Link:
Organism Gene ID SwissProt
Human 7056; P07204;
Mouse P15306;
Background:
disease:Defects in THBD are the cause of thrombophilia due to thrombomodulin defect (THR-THBDD) [MIM:188040]. THR-THBDD is a hemostatic disorder characterized by a tendency to thrombosis.,function:Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated.,online information:Thrombomodulin,online information:Thrombomodulin entry,PTM:N-glycosylated.,PTM:The iron and 2-oxoglutarate dependent 3-hydroxylation of aspartate and asparagine is (R) stereospecific within EGF domains.,similarity:Contains 1 C-type lectin domain.,similarity:Contains 6 EGF-like domains.,tissue specificity:Endothelial cells are unique in synthesizing thrombomodulin.,
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Function:
response to molecule of bacterial origin, female pregnancy, blood coagulation, hemostasis, response to radiation,response to wounding, response to bacterium, response to abiotic stimulus, response to organic substance, response to X-ray, response to ionizing radiation, response to lipopolysaccharide, wound healing, coagulation, regulation of body fluid levels, response to cAMP,
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Cellular Localization:
Membrane; Single-pass type I membrane protein.
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Tissue Expression:
Endothelial cells are unique in synthesizing thrombomodulin.
show all
Catalog: KE1252
Size
Price
Status
Qty.
5*96well
$1,850.00
3 weeks

0

2*96well
$740.00
3 weeks

0

96well
$370.00
3 weeks

0

Add to cart

Collected

Collect

Customized Service

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