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Human MIF ELISA Kit

-KE1237

Catalog: KE1237
Size
Price
Status
Qty.
5*96well
$1,850.00
3 weeks

0

2*96well
$740.00
3 weeks

0

96well
$370.00
3 weeks

0

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Main Information
Reactivity

Human

Applications

ELISA

Conjugate/Modification


Unmodified

Detailed Information
Specificity
Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma
Storage
2-8°C/6 months
Modification
Unmodified
Sample Type
Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma
Detection Method
Colorimetric
Sensitivity
32-2000 pg/ml
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Antigen&Target Information
Specificity:
Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma
show all
Gene Name:
MIF
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Protein Name:
Macrophage migration inhibitory factor
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Other Name:
MIF ;
GLIF ;
MMIF ;
Macrophage migration inhibitory factor ;
MIF ;
Glycosylation-inhibiting factor ;
GIF ;
L-dopachrome isomerase ;
L-dopachrome tautomerase ;
Phenylpyruvate tautomerase
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Database Link:
Organism Gene ID SwissProt
Human 4282; P14174;
Mouse P34884;
Background:
catalytic activity:Keto-phenylpyruvate = enol-phenylpyruvate.,disease:Genetic variations in MIF are associated with susceptibility to systemic juvenile rheumatoid arthritis [MIM:604302]. Systemic juvenile rheumatoid arthritis is juvenile chronic arthritis associated with severe, debilitating, extraarticular features, and occasionally fatal complications. Despite medical treatment, many children still experience early joint destruction, necessitating surgical replacement.,function:The expression of MIF at sites of inflammation suggest a role for the mediator in regulating the function of macrophage in host defense. Also acts as a phenylpyruvate tautomerase.,similarity:Belongs to the MIF family.,subunit:Homotrimer. Interacts with COPS5 and BNIPL.,
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Function:
prostaglandin biosynthetic process, regulation of leukocyte activation, protein complex assembly, fatty acid metabolic process, fatty acid biosynthetic process, unsaturated fatty acid biosynthetic process, icosanoid metabolic process,prostanoid metabolic process, prostaglandin metabolic process, defense response, inflammatory response, immune response, cell surface receptor linked signal transduction, cell proliferation, lipid biosynthetic process, response to wounding, regulation of cell death, organic acid biosynthetic process, unsaturated fatty acid metabolic process,regulation of apoptosis, regulation of macrophage activation, negative regulation of apoptosis, regulation of programmed cell death, negative regulation of programmed cell death, macromolecular complex subunit organization,innate immune response, carboxylic acid biosynthetic process, icosanoid biosynthetic process, prostanoid biosynthetic process, regulation of cell activation, protein oligomerization, protein homooligomerization, negative regulation of cell death, macromolecular complex assembly, protein trimerization, protein homotrimerization, protein complex biogenesis,
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Cellular Localization:
Secreted . Cytoplasm . Does not have a cleavable signal sequence and is secreted via a specialized, non-classical pathway. Secreted by macrophages upon stimulation by bacterial lipopolysaccharide (LPS), or by M.tuberculosis antigens. .
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Catalog: KE1237
Size
Price
Status
Qty.
5*96well
$1,850.00
3 weeks

0

2*96well
$740.00
3 weeks

0

96well
$370.00
3 weeks

0

Add to cart

Collected

Collect

Customized Service

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