Catalog: KE1212
Size
Price
Status
Qty.
5*96well
$1,850.00
3 weeks
0
2*96well
$740.00
3 weeks
0
96well
$370.00
3 weeks
0
Add to cart
Collected
Collect
Main Information
Reactivity
Human
Applications
ELISA
Conjugate/Modification
Unmodified
Detailed Information
Specificity
Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma
Storage
2-8°C/6 months
Modification
Unmodified
Sample Type
Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma
Detection Method
Colorimetric
Sensitivity
32-2000 pg/ml
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Antigen&Target Information
Specificity:
Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma
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Gene Name:
CFD
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Protein Name:
Complement factor D
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Other Name:
CFD ;
DF ;
PFD ;
Complement factor D ;
Adipsin ;
C3 convertase activator ;
Properdin factor D
DF ;
PFD ;
Complement factor D ;
Adipsin ;
C3 convertase activator ;
Properdin factor D
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Background:
catalytic activity:Selective cleavage of Arg-|-Lys bond in complement factor B when in complex with complement subcomponent C3b or with cobra venom factor.,disease:Defects in CFD are the cause of complement factor D deficiency [MIM:134350]. This deficiency predisposes to invasive meningococcal disease.,function:Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway.,online information:CFD mutation db,similarity:Belongs to the peptidase S1 family.,similarity:Contains 1 peptidase S1 domain.,
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Function:
immune effector process, activation of immune response, acute inflammatory response, activation of plasma proteins involved in acute inflammatory response, positive regulation of immune system process, proteolysis, defense response, inflammatory response, immune response, complement activation, complement activation, alternative pathway, humoral immune response, cell surface receptor linked signal transduction, Notch signaling pathway,response to wounding, protein processing, innate immune response, positive regulation of response to stimulus,positive regulation of immune response, protein maturation, protein maturation by peptide bond cleavage,
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Cellular Localization:
Secreted.
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Reference Citation({{totalcount}})
Catalog: KE1212
Size
Price
Status
Qty.
5*96well
$1,850.00
3 weeks
0
2*96well
$740.00
3 weeks
0
96well
$370.00
3 weeks
0
Add to cart
Collected
Collect
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