Catalog: YP1315
Size
Price
Status
Qty.
200μL
$600.00
3 weeks
0
100μL
$340.00
3 weeks
0
50μL
$190.00
3 weeks
0
Add to cart
Collected
Collect
Main Information
Target
DNAJC2 Phospho Ser47
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB
MW
68kD (Observed)
Conjugate/Modification
phosphate
Detailed Information
Recommended Dilution Ratio
WB 1:1000-2000
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
This antibody detects endogenous levels of Human Mouse Rat DNAJC2/MPP11 (phospho-Ser47)
Purification
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Storage
-15°C to -25°C/1 year (Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
68kD
Modification
phosphate
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
Synthesized phosho peptide around human DNAJC2 and MPP11 (Ser47)
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Specificity:
This antibody detects endogenous levels of Human Mouse Rat DNAJC2/MPP11 (phospho-Ser47)
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Gene Name:
DNAJC2 MPHOSPH11 MPP11 ZRF1
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Protein Name:
DnaJ homolog subfamily C member 2
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Other Name:
DnaJ homolog subfamily C member 2 ;
M-phase phosphoprotein 11 ;
Zuotin-related factor 1 ;
M-phase phosphoprotein 11 ;
Zuotin-related factor 1 ;
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Database Link:
Background:
This gene is a member of the M-phase phosphoprotein (MPP) family. The gene encodes a phosphoprotein with a J domain and a Myb DNA-binding domain which localizes to both the nucleus and the cytosol. The protein is capable of forming a heterodimeric complex that associates with ribosomes , acting as a molecular chaperone for nascent polypeptide chains as they exit the ribosome. This protein was identified as a leukemia-associated antigen and expression of the gene is upregulated in leukemic blasts. Also , chromosomal aberrations involving this gene are associated with primary head and neck squamous cell tumors. This gene has a pseudogene on chromosome 6. Alternatively spliced variants which encode different protein isoforms have been described. [provided by RefSeq , Jul 2008] ,
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Function:
PTM:Phosphorylated in M (mitotic) phase. ,similarity:Contains 1 J domain. ,similarity:Contains 2 SANT domains. ,
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Cellular Localization:
Nucleus . Cytoplasm , cytosol .
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Tissue Expression:
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Reference Citation({{totalcount}})
Catalog: YP1315
Size
Price
Status
Qty.
200μL
$600.00
3 weeks
0
100μL
$340.00
3 weeks
0
50μL
$190.00
3 weeks
0
Add to cart
Collected
Collect
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