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Human P-Cadherin ELISA Kit

-KE1158

Catalog: KE1158
Size
Price
Status
Qty.
5*96well
$1,850.00
3 weeks

0

2*96well
$740.00
3 weeks

0

96well
$370.00
3 weeks

0

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Main Information
Reactivity

Human

Applications

ELISA

Conjugate/Modification


Unmodified

Detailed Information
Specificity
Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma
Storage
2-8°C/6 months
Modification
Unmodified
Sample Type
Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma
Detection Method
Colorimetric
Sensitivity
63-4000 pg/ml
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Antigen&Target Information
Specificity:
Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma
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Gene Name:
CDH3
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Protein Name:
Cadherin-3
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Other Name:
CDH3 ;
CDHP ;
Cadherin-3 ;
Placental cadherin ;
P-cadherin
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Database Link:
Organism Gene ID SwissProt
Human 1001; P22223;
Mouse P10287;
Background:
disease:Defects in CDH3 are the cause of ectodermal dysplasia with ectrodactyly and macular dystrophy (EEM) [MIM:225280]; also known as EEM syndrome, Albrectsen-Svendsen syndrome or Ohdo-Hirayama-Terawaki syndrome. Ectodermal dysplasia defines a heterogeneous group of disorders due to abnormal development of two or more ectodermal structures. EEM is an autosomal recessive condition characterized by features of ectodermal dysplasia such as sparse eyebrows and scalp hair, and selective tooth agenesis associated with macular dystrophy and ectrodactyly.,disease:Defects in CDH3 are the cause of hypotrichosis with juvenile macular dystrophy (HJMD) [MIM:601553]. HJMD is a rare autosomal recessive disorder characterized by early hair loss heralding severe degenerative changes of the retinal macula and culminating in blindness during the second to third decade of life.,function:Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.,online information:Retina International's Scientific Newsletter,similarity:Contains 5 cadherin domains.,subunit:Interacts with CDCP1.,tissue specificity:Expressed in some normal epithelial tissues and in some carcinoma cell lines.,
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Function:
cell adhesion, homophilic cell adhesion, sensory perception, visual perception, response to wounding, cell-cell adhesion, biological adhesion, wound healing, response to drug, neurological system process, cognition, sensory perception of light stimulus,
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Cellular Localization:
Cell membrane; Single-pass type I membrane protein.
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Tissue Expression:
Expressed in some normal epithelial tissues and in some carcinoma cell lines.
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Catalog: KE1158
Size
Price
Status
Qty.
5*96well
$1,850.00
3 weeks

0

2*96well
$740.00
3 weeks

0

96well
$370.00
3 weeks

0

Add to cart

Collected

Collect

Customized Service

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