Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma

IL20

Interleukin-20

IL20 ;
ZCYTO10 ;
Interleukin-20 ;
IL-20 ;
Cytokine Zcyto10

function:Cytokine that may be involved in epidermal function and psoriasis. Acts through STAT3.,similarity:Belongs to the IL-10 family.,tissue specificity:Expressed at very low levels in skin, trachea, and other tissues.,

regulation of protein amino acid phosphorylation, positive regulation of protein amino acid phosphorylation, positive regulation of signal transduction, positive regulation of phosphorus metabolic process, positive regulation of macromolecule metabolic process, regulation of protein kinase cascade, positive regulation of cell communication,positive regulation of protein kinase cascade, regulation of phosphate metabolic process, regulation of epithelial cell differentiation, positive regulation of epithelial cell differentiation, regulation of protein modification process, positive regulation of protein modification process, regulation of response to external stimulus, regulation of cellular protein metabolic process, positive regulation of cellular protein metabolic process, regulation of phosphorylation, positive regulation of phosphorylation, regulation of tyrosine phosphorylation of STAT protein, regulation of tyrosine phosphorylation of Stat3 protein, positive regulation of tyrosine phosphorylation of Stat3 protein, positive regulation of tyrosine phosphorylation of STAT protein, positive regulation of cell differentiation, regulation of epidermal cell differentiation, positive regulation of epidermal cell differentiation, regulation of keratinocyte differentiation, positive regulation of keratinocyte differentiation, regulation of epidermis development, positive regulation of epidermis development, positive regulation of phosphate metabolic process, regulation of JAK-STAT cascade, positive regulation of JAK-STAT cascade, regulation of inflammatory response, regulation of peptidyl-tyrosine phosphorylation, positive regulation of peptidyl-tyrosine phosphorylation, positive regulation of developmental process, regulation of phosphorus metabolic process, positive regulation of protein metabolic process,

Secreted.

Expressed in most tissues and five major cell types: epithelial cells (primarily skin, buccal mucosa, tongue, nasal mucosa, lung, ureter, breast, prostate, fallopian tube, and adrenal gland), myoepithelial cells (mainly prostate), endothelial cells (mainly in small vessels or capillaries), macrophages, and skeletal muscle. Isoform 2 was detected in the lung tissue only.