CD19 (Phospho Tyr500) Rabbit pAb

-YP1837

Catalog: YP1837
Size
Price
Status
Qty.
200μL
$936.00
In stock

0

100μL
$560.00
In stock

0

50μL
$300.00
In stock

0

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Main Information
Target

CD19 Phospho Tyr500

Host Species

Rabbit

Reactivity

Human, Mouse

Applications

IHC, WB

MW

61kD (Observed)

Conjugate/Modification


Phospho

Detailed Information
Recommended Dilution Ratio
WB 1:500-2000; IHC 1:50-200
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Specificity
This antibody detects endogenous levels of CD19 (Phospho Tyr500) Rabbit pAb at Human, Mouse.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):QSyED
Purification
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
61kD
Modification
Phospho
Clonality
Polyclonal
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from human CD19 (Phospho Tyr500)
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Specificity:
This antibody detects endogenous levels of CD19 (Phospho Tyr500) Rabbit pAb at Human, Mouse.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):QSyED
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Gene Name:
CD19
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Protein Name:
B-lymphocyte antigen CD19 (B-lymphocyte surface antigen B4) (Differentiation antigen CD19) (T-cell surface antigen Leu-12) (CD antigen CD19)
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Other Name:
B-lymphocyte antigen CD19 ;
B-lymphocyte surface antigen B4 ;
Differentiation antigen CD19 ;
T-cell surface antigen Leu-12 ;
CD antigen CD19 ;
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Database Link:
Organism Gene ID SwissProt
Human 930; P15391;
Mouse 12478; P25918;
Background:
CD19 molecule(CD19) Homo sapiens Lymphocytes proliferate and differentiate in response to various concentrations of different antigens. The ability of the B cell to respond in a specific, yet sensitive manner to the various antigens is achieved with the use of low-affinity antigen receptors. This gene encodes a cell surface molecule which assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation. [provided by RefSeq, Jul 2008],
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Function:
Disease:Defects in CD19 are a cause of hypogammaglobulinemia [MIM:107265].,Function:Assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation.,online information:CD19 mutation db,PTM:Phosphorylated on serine and threonine upon DNA damage, probably by ATM or ATR. Phosphorylated on tyrosine following B-cell activation.,similarity:Contains 2 Ig-like C2-type (immunoglobulin-like) domains.,subunit:Forms a complex with CD21, CD81 and CD225 in the membrane of mature B cells. Interacts with VAV. Interacts with GRB2 and SOS when phosphorylated on Tyr-348 and/or Tyr-378. Interacts with PLCG2 when phosphorylated on Tyr-409.,
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Cellular Localization:
Cell membrane ; Single-pass type I membrane protein . Membrane raft ; Single-pass type I membrane protein .
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Research Areas:
>>PI3K-Akt signaling pathway ;
>>Hematopoietic cell lineage ;
>>B cell receptor signaling pathway ;
>>Epstein-Barr virus infection ;
>>Primary immunodeficiency
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Catalog: YP1837
Size
Price
Status
Qty.
200μL
$936.00
In stock

0

100μL
$560.00
In stock

0

50μL
$300.00
In stock

0

Add to cart

Collected

Collect

Customized Service

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