Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma

BMP2

Bone morphogenetic protein 2

BMP2 ;
BMP2A ;
Bone morphogenetic protein 2 ;
BMP-2 ;
Bone morphogenetic protein 2A ;
BMP-2A

function:Induces cartilage and bone formation.,online information:Bone morphogenetic protein 2 entry,similarity:Belongs to the TGF-beta family.,subunit:Homodimer; disulfide-linked. Interacts with GREM2 (By similarity) and SOSTDC1.,tissue specificity:Particularly abundant in lung, spleen and colon and in low but significant levels in heart, brain, placenta, liver, skeletal muscle, kidney, pancreas, prostate, ovary and small intestine.,

cell morphogenesis, cell morphogenesis involved in differentiation, skeletal system development, ossification,osteoblast differentiation, urogenital system development, metanephros development, ureteric bud development,branching involved in ureteric bud morphogenesis, morphogenesis of a branching structure, kidney development,epithelial to mesenchymal transition, regulation of protein amino acid phosphorylation, positive regulation of protein amino acid phosphorylation, morphogenesis of an epithelium, heart morphogenesis, regulation of transcription, DNA-dependent, regulation of transcription from RNA polymerase II promoter, protein amino acid phosphorylation,phosphorus metabolic process, phosphate metabolic process, defense response, inflammatory response, cell surface receptor linked signal transduction, enzyme linked receptor protein signaling pathway, transmembrane receptor protein serine/threonine kinase signaling pathway, cell-cell signaling, heart development, response to nutrient,negative regulation of cell proliferation, response to wounding, response to mechanical stimulus, response to abiotic stimulus, negative regulation of biosynthetic process, positive regulation of biosynthetic process, positive regulation of signal transduction, response to extracellular stimulus, positive regulation of macromolecule biosynthetic process,negative regulation of macromolecule biosynthetic process, positive regulation of phosphorus metabolic process,positive regulation of macromolecule metabolic process, negative regulation of macromolecule metabolic process,positive regulation of gene expression, negative regulation of gene expression, positive regulation of cell communication, positive regulation of cell development, positive regulation of pathway-restricted SMAD protein phosphorylation, regulation of gliogenesis, positive regulation of gliogenesis, mesenchymal cell development,phosphorylation, negative regulation of transcription, regulation of phosphate metabolic process, regulation of ossification, regulation of bone mineralization, positive regulation of bone mineralization, BMP signaling pathway,negative regulation of cellular biosynthetic process, positive regulation of cellular biosynthetic process, regulation of protein modification process, positive regulation of protein modification process, response to nutrient levels,regulation of cellular protein metabolic process, positive regulation of cellular protein metabolic process, multicellular organism reproduction, response to retinoic acid, negative regulation of gene-specific transcription, regulation of gene-specific transcription, cellular component morphogenesis, response to vitamin A, response to vitamin, cardiac cell differentiation, tube morphogenesis, tube development, growth, regulation of cell proliferation, regulation of phosphorylation, positive regulation of phosphorylation, odontogenesis of dentine-containing tooth, odontogenesis,ovulation cycle, cell fate commitment, regulation of transcription, positive regulation of cell differentiation, regulation of osteoblast differentiation, positive regulation of osteoblast differentiation, regulation of glial cell differentiation,positive regulation of glial cell differentiation, positive regulation of ossification, negative regulation of cell cycle,negative regulation of transcription, DNA-dependent, positive regulation of transcription, DNA-dependent, negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process, positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process, positive regulation of phosphate metabolic process, positive regulation of transcription, positive regulation of transcription from RNA polymerase II promoter, rhythmic process,reproductive process in a multicellular organism, regulation of astrocyte differentiation, positive regulation of astrocyte differentiation, tissue morphogenesis, branching morphogenesis of a tube, mesenchymal cell differentiation, regulation of neurogenesis, positive regulation of neurogenesis, positive regulation of developmental process, negative regulation of nitrogen compound metabolic process, positive regulation of nitrogen compound metabolic process,regulation of phosphorus metabolic process, cartilage development, positive regulation of multicellular organismal process, positive regulation of protein metabolic process, regulation of RNA metabolic process, negative regulation of RNA metabolic process, positive regulation of RNA metabolic process, regulation of cell cycle, regulation of nervous system development, regulation of cell development, cardiac epithelial to mesenchymal transition, bone development,pathway-restricted SMAD protein phosphorylation, regulation of pathway-restricted SMAD protein phosphorylation,epithelium development, mesenchyme development, epithelial tube morphogenesis, ureteric bud morphogenesis,regulation of biomineral formation, positive regulation of biomineral formation,

Secreted.

Particularly abundant in lung, spleen and colon and in low but significant levels in heart, brain, placenta, liver, skeletal muscle, kidney, pancreas, prostate, ovary and small intestine.