Catalog: YP1756
Size
Price
Status
Qty.
200μL
$600.00
In stock
0
100μL
$340.00
In stock
0
50μL
$190.00
In stock
0
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Collected
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Main Information
Target
CRMP1 Phospho Tyr504
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB
MW
63kD (Calculated)
Conjugate/Modification
Phospho
Detailed Information
Recommended Dilution Ratio
WB 1:500-2000
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
This antibody detects endogenous levels of CRMP-1 (Phospho-Tyr504) at Human, Mouse,Rat.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):PVyEV
Purification
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Calculated)
63kD
Modification
Phospho
Clonality
Polyclonal
Isotype
IgG
Antigen&Target Information
Immunogen:
Synthesized peptide derived from human CRMP-1 (Phospho-Tyr504)
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Specificity:
This antibody detects endogenous levels of CRMP-1 (Phospho-Tyr504) at Human, Mouse,Rat.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):PVyEV
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Gene Name:
CRMP1 DPYSL1 ULIP3
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Protein Name:
Dihydropyrimidinase-related protein 1
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Other Name:
DPYL1 ;
Dihydropyrimidinase-related protein 1 ;
DRP-1 ;
Collapsin response mediator protein 1 ;
CRMP-1 ;
Unc-33-like phosphoprotein 3 ;
ULIP-3 ;
Dihydropyrimidinase-related protein 1 ;
DRP-1 ;
Collapsin response mediator protein 1 ;
CRMP-1 ;
Unc-33-like phosphoprotein 3 ;
ULIP-3 ;
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Database Link:
Background:
This gene encodes a member of a family of cytosolic phosphoproteins expressed exclusively in the nervous system. The encoded protein is thought to be a part of the semaphorin signal transduction pathway implicated in semaphorin-induced growth cone collapse during neural development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008],
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Function:
Function:Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration.,similarity:Belongs to the DHOase family. Hydantoinase/dihydropyrimidinase subfamily.,subcellular location:Associated with centrosomes and the mitotic spindle during metaphase.,subunit:Homotetramer, and heterotetramer with DPYSL2, DPYSL3, DPYSL4 or DPYSL5. Interacts with PLXNA1.,tissue specificity:Brain.,
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Cellular Localization:
Cytoplasm . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, spindle . Cell projection, growth cone . Cytoplasm, cytoskeleton . Perikaryon . Associated with centrosomes and the mitotic spindle during metaphase (PubMed:11562390). Colocalizes with FLNA and tubulin in the central region of DRG neuron growth cone (By similarity). Following SEMA3A stimulation of DRG neurons, colocalizes with F-actin (By similarity). .
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Tissue Expression:
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Reference Citation({{totalcount}})
Catalog: YP1756
Size
Price
Status
Qty.
200μL
$600.00
In stock
0
100μL
$340.00
In stock
0
50μL
$190.00
In stock
0
Add to cart
Collected
Collect
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