Catalog: YP1728
Size
Price
Status
Qty.
200μL
$600.00
In stock
0
100μL
$340.00
In stock
0
50μL
$190.00
In stock
0
Add to cart
Collected
Collect
Main Information
Target
EIF6 Phospho Ser235
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB
MW
27kD (Calculated)
Conjugate/Modification
Phospho
Detailed Information
Recommended Dilution Ratio
WB 1:500-2000
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
This antibody detects endogenous levels of EIF6 (Phospho-Ser235) at Human, Mouse,Rat.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):ATsMR
Purification
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Calculated)
27kD
Modification
Phospho
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from human EIF6 (Phospho-Ser235)
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Specificity:
This antibody detects endogenous levels of EIF6 (Phospho-Ser235) at Human, Mouse,Rat.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):ATsMR
show all
Gene Name:
EIF6 EIF3A ITGB4BP OK/SW-cl.27
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Protein Name:
EIF6 (Phospho-Ser235)
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Other Name:
IF6 ;
Eukaryotic translation initiation factor 6 ;
eIF-6 ;
B ;
2 ;
GCN homolog ;
B4 integrin interactor ;
CAB ;
p27 ;
BBP ;
Eukaryotic translation initiation factor 6 ;
eIF-6 ;
B ;
2 ;
GCN homolog ;
B4 integrin interactor ;
CAB ;
p27 ;
BBP ;
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Database Link:
Background:
Hemidesmosomes are structures which link the basal lamina to the intermediate filament cytoskeleton. An important functional component of hemidesmosomes is the integrin beta-4 subunit (ITGB4), a protein containing two fibronectin type III domains. The protein encoded by this gene binds to the fibronectin type III domains of ITGB4 and may help link ITGB4 to the intermediate filament cytoskeleton. The encoded protein, which is insoluble and found both in the nucleus and in the cytoplasm, can function as a translation initiation factor and prevent the association of the 40S and 60S ribosomal subunits. Multiple non-protein coding transcript variants and variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2012],
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Function:
Function:Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex.,similarity:Belongs to the eIF-6 family.,subunit:Monomer.,
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Cellular Localization:
Cytoplasm. Nucleus, nucleolus. Shuttles between cytoplasm and nucleus/nucleolus.
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Tissue Expression:
Research Areas:
>>Ribosome biogenesis in eukaryotes
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Reference Citation({{totalcount}})
Catalog: YP1728
Size
Price
Status
Qty.
200μL
$600.00
In stock
0
100μL
$340.00
In stock
0
50μL
$190.00
In stock
0
Add to cart
Collected
Collect
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