Catalog: YP1470
Size
Price
Status
Qty.
200μL
$600.00
In stock
0
100μL
$340.00
In stock
0
50μL
$190.00
In stock
0
Add to cart
Collected
Collect
Main Information
Target
RPA2 Phospho Ser8
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB
MW
32kD (Observed)
Conjugate/Modification
Phospho
Detailed Information
Recommended Dilution Ratio
WB 1:1000-2000
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
This antibody detects endogenous levels of Human RPA32 or RPA2 (phospho-Ser8)
Purification
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
32kD
Modification
Phospho
Clonality
Polyclonal
Isotype
IgG
Related Products
Primary Antibodies
RPA32/RPA2 Rabbit pAb
YT4170
More→
Primary Antibodies
RPA32/RPA2 (Phospho Thr21) Rabbit pAb
YP0743
More→
Primary Antibodies
.jpg)
RPA32/RPA2 (Phospho Ser33) Rabbit pAb
YP0476
More→
ELISA Kits
Total RFA2 Cell-Based Colorimetric ELISA Kit
KA4267C
More→
ELISA Kits
RFA2 (Phospho Ser33) Cell-Based Colorimetric ELISA Kit
KA1758C
More→
ELISA Kits
RFA2 (Phospho Thr21) Cell-Based Colorimetric ELISA Kit
KA1472C
More→
Antigen&Target Information
Immunogen:
Synthesized phosho peptide around human RPA32 and RPA2 (Ser8)
show all
Specificity:
This antibody detects endogenous levels of Human RPA32 or RPA2 (phospho-Ser8)
show all
Gene Name:
RPA2 REPA2 RPA32 RPA34
show all
Protein Name:
RPA32/RPA2 (Ser8)
show all
Other Name:
Replication protein A 32 kDa subunit ;
RP-A p32 ;
Replication factor A protein 2 ;
RF-A protein 2 ;
Replication protein A 34 kDa subunit ;
RP-A p34 ;
RP-A p32 ;
Replication factor A protein 2 ;
RF-A protein 2 ;
Replication protein A 34 kDa subunit ;
RP-A p34 ;
show all
Function:
Function:Required for DNA recombination, repair and replication. The activity of RP-A is mediated by single-stranded DNA binding and protein interactions.,PTM:Phosphorylated in a cell-cycle-dependent manner (from the S phase until mitosis). Phosphorylated by ATR upon DNA damage, which promotes its translocation to nuclear foci. Can be phosphorylated in vitro by PRKDC/DNA-PK in the presence of Ku and DNA, and by CDC2.,subcellular location:Also present in PML nuclear bodies. Redistributes to discrete nuclear foci upon DNA damage.,subunit:Heterotrimer of 70, 32 and 14 kDa chains. The DNA-binding activity may reside exclusively on the 70 kDa subunit. Binds to SERTAD3/RBT1. Interacts with TIPIN.,
show all
Cellular Localization:
Nucleus . Nucleus, PML body . Redistributes to discrete nuclear foci upon DNA damage in an ATR-dependent manner. .
show all
Tissue Expression:
show all
Research Areas:
>>DNA replication ;
>>Nucleotide excision repair ;
>>Mismatch repair ;
>>Homologous recombination ;
>>Fanconi anemia pathway
>>Nucleotide excision repair ;
>>Mismatch repair ;
>>Homologous recombination ;
>>Fanconi anemia pathway
show all
Reference Citation({{totalcount}})
Catalog: YP1470
Size
Price
Status
Qty.
200μL
$600.00
In stock
0
100μL
$340.00
In stock
0
50μL
$190.00
In stock
0
Add to cart
Collected
Collect
Recently Viewed Products
Clear allPRODUCTS
CUSTOMIZED
ABOUT US
Toggle night Mode
{{pinfoXq.title || ''}}
Catalog: {{pinfoXq.catalog || ''}}
Filter：
All
{{item.name}}
{{pinfo.title}}
-{{pinfo.catalog}}
Main Information
Target
{{pinfo.target}}
Reactivity
{{pinfo.react}}
Applications
{{pinfo.applicat}}
Conjugate/Modification
{{pinfo.coupling}}/{{pinfo.modific}}
MW (kDa)
{{pinfo.mwcalc}}
Host Species
{{pinfo.hostspec}}
Isotype
{{pinfo.isotype}}
Product {{index}}/{{pcount}}
Prev
Next
{{pvTitle}}
Scroll wheel zooms the picture
{{pvDescr}}