Catalog: YP1268
Size
Price
Status
Qty.
200μL
$600.00
In stock
0
100μL
$340.00
In stock
0
50μL
$190.00
In stock
0
Add to cart
Collected
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Main Information
Target
ATG14 Phospho Ser29
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
WB
MW
55kD (Observed)
Conjugate/Modification
Phospho
Detailed Information
Recommended Dilution Ratio
WB 1:1000-2000
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
This antibody detects endogenous levels of Human Mouse Atg14 (phospho-Ser29)
Purification
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
55kD
Modification
Phospho
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
Synthesized phosho peptide around human Atg14 (Ser29)
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Specificity:
This antibody detects endogenous levels of Human Mouse Atg14 (phospho-Ser29)
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Gene Name:
ATG14 KIAA0831 ATG14L
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Protein Name:
Atg14 (Ser29)
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Other Name:
Beclin 1-associated autophagy-related key regulator ;
Barkor ;
Autophagy-related protein 14-like protein ;
Atg14L ;
Barkor ;
Autophagy-related protein 14-like protein ;
Atg14L ;
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Database Link:
Function:
miscellaneous:The sequence shown here is derived from an EMBL/GenBank/DDBJ third party annotation (TPA) entry.,
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Cellular Localization:
Cytoplasm . Endoplasmic reticulum membrane ; Peripheral membrane protein . Preautophagosomal structure membrane ; Peripheral membrane protein . Cytoplasmic vesicle, autophagosome membrane ; Peripheral membrane protein . Cytosolic under nutrient-rich conditions (PubMed:19050071). Following autophagy stimuli, such as starvation or rapamycin induction, predominantly detected in cytoplasmic foci, identified as isolation membranes and autophagosomes (PubMed:19050071). Accumulates on highly curved PtdIns(3)P enriched autophagic membrane via its BATS domain to sense and maintain membrane curvature (By similarity). Localizes also to discrete punctae along the ciliary axoneme and to the base of the ciliary axoneme (By similarity). .
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Tissue Expression:
Research Areas:
>>Autophagy - animal ;
>>Alzheimer disease ;
>>Amyotrophic lateral sclerosis ;
>>Huntington disease ;
>>Spinocerebellar ataxia ;
>>Pathways of neurodegeneration - multiple diseases ;
>>Shigellosis ;
>>Kaposi sarcoma-associated herpesvirus infection
>>Alzheimer disease ;
>>Amyotrophic lateral sclerosis ;
>>Huntington disease ;
>>Spinocerebellar ataxia ;
>>Pathways of neurodegeneration - multiple diseases ;
>>Shigellosis ;
>>Kaposi sarcoma-associated herpesvirus infection
show all
Signaling Pathway
Cellular Processes >> Transport and catabolism >> Autophagy - animal
Human Diseases >> Neurodegenerative disease >> Alzheimer disease
Human Diseases >> Neurodegenerative disease >> Amyotrophic lateral sclerosis
Human Diseases >> Neurodegenerative disease >> Huntington disease
Human Diseases >> Neurodegenerative disease >> Spinocerebellar ataxia
Human Diseases >> Neurodegenerative disease >> Pathways of neurodegeneration - multiple diseases
Reference Citation({{totalcount}})
Catalog: YP1268
Size
Price
Status
Qty.
200μL
$600.00
In stock
0
100μL
$340.00
In stock
0
50μL
$190.00
In stock
0
Add to cart
Collected
Collect
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