Catalog: YP1195
Size
Price
Status
Qty.
200μL
$600.00
In stock
0
100μL
$340.00
In stock
0
50μL
$190.00
In stock
0
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Collected
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Main Information
Target
NFAT5 Phospho Ser1197
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
WB, IHC, IF, ELISA
MW
166kD (Calculated)
Conjugate/Modification
Phospho
Detailed Information
Recommended Dilution Ratio
WB 1:500-2000; IHC 1:50-300; IF 1:200-1:1000; ELISA 5000-1:20000;
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
Phospho-NFAT5 (S1197) Polyclonal Antibody detects endogenous levels of NFAT5 protein only when phosphorylated at S1197.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):MLsQE
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Calculated)
166kD
Modification
Phospho
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
The antiserum was produced against synthesized peptide derived from human NFAT5 around the phosphorylation site of Ser1197. AA range:1171-1220
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Specificity:
Phospho-NFAT5 (S1197) Polyclonal Antibody detects endogenous levels of NFAT5 protein only when phosphorylated at S1197.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):MLsQE
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Gene Name:
NFAT5
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Protein Name:
Nuclear factor of activated T-cells 5
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Other Name:
NFAT5 ;
KIAA0827 ;
TONEBP ;
Nuclear factor of activated T-cells 5 ;
NF-AT5 ;
T-cell transcription factor NFAT5 ;
Tonicity-responsive enhancer-binding protein ;
TonE-binding protein ;
TonEBP
KIAA0827 ;
TONEBP ;
Nuclear factor of activated T-cells 5 ;
NF-AT5 ;
T-cell transcription factor NFAT5 ;
Tonicity-responsive enhancer-binding protein ;
TonE-binding protein ;
TonEBP
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Background:
The product of this gene is a member of the nuclear factors of activated T cells family of transcription factors. Proteins belonging to this family play a central role in inducible gene transcription during the immune response. This protein regulates gene expression induced by osmotic stress in mammalian cells. Unlike monomeric members of this protein family, this protein exists as a homodimer and forms stable dimers with DNA elements. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
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Function:
Alternative products:Experimental confirmation may be lacking for some isoforms,Function:Plays a role in the inducible expression of genes. Regulates hypertonicity-induced cellular accumulation of osmolytes.,similarity:Contains 1 RHD (Rel-like) domain.,subunit:Does not bind with Fos and Jun transcription factors. But might be capable of forming stable dimers with DNA elements.,tissue specificity:Highest levels in skeletal muscle, brain, heart and peripheral blood leukocytes. Also expressed in placenta, lung, liver, kidney, pancreas, spleen, thymus, prostate, testis, ovary, small intestine and colon.,
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Cellular Localization:
Nucleus . Cytoplasm . Nuclear distribution increases under hypertonic conditions. .
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Tissue Expression:
Reference Citation({{totalcount}})
Catalog: YP1195
Size
Price
Status
Qty.
200μL
$600.00
In stock
0
100μL
$340.00
In stock
0
50μL
$190.00
In stock
0
Add to cart
Collected
Collect
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