Catalog: YP1161
Size
Price
Status
Qty.
200μL
$600.00
In stock
0
100μL
$340.00
In stock
0
50μL
$190.00
In stock
0
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Main Information
Target
TGFβ RIII Phospho Thr842
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
IHC, IF, ELISA
MW
93kD (Calculated)
Conjugate/Modification
Phospho
Detailed Information
Recommended Dilution Ratio
IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:5000; Not yet tested in other applications.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
Phospho-TGFβ RIII (T842) Polyclonal Antibody detects endogenous levels of TGFβ RIII protein only when phosphorylated at T842.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):QStPC
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Calculated)
93kD
Modification
Phospho
Clonality
Polyclonal
Isotype
IgG
Related Products
Primary Antibodies
TGFβ RIII Rabbit pAb
YT4630
More→
Primary Antibodies
TGFβ RIII (Phospho Thr842) Rabbit pAb
YP1161
More→
ELISA Kits
Human TGFβ-R3 ELISA Kit
KE1166
More→
ELISA Kits
Total TGFβ RIII Cell-Based Colorimetric ELISA Kit
KA3389C
More→
Antigen&Target Information
Immunogen:
The antiserum was produced against synthesized peptide derived from human TGF beta Receptor III around the phosphorylation site of Thr842. AA range:801-850
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Specificity:
Phospho-TGFβ RIII (T842) Polyclonal Antibody detects endogenous levels of TGFβ RIII protein only when phosphorylated at T842.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):QStPC
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Gene Name:
TGFBR3
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Protein Name:
Transforming growth factor beta receptor type 3
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Other Name:
TGFBR3 ;
Transforming growth factor beta receptor type 3 ;
TGF-beta receptor type 3 ;
TGFR-3 ;
Betaglycan ;
Transforming growth factor beta receptor III ;
TGF-beta receptor type III
Transforming growth factor beta receptor type 3 ;
TGF-beta receptor type 3 ;
TGFR-3 ;
Betaglycan ;
Transforming growth factor beta receptor III ;
TGF-beta receptor type III
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Database Link:
Background:
This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.[provided by RefSeq, Sep 2010],
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Function:
Function:Binds to TGF-beta. Could be involved in capturing and retaining TGF-beta for presentation to the signaling receptors.,PTM:Extensively modified by glycosaminoglycan groups (GAG).,similarity:Contains 1 ZP domain.,subcellular location:Exists both as a membrane-bound form and as soluble form in serum and in the extracellular matrix.,subunit:Interacts with TCTEX1D4.,
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Cellular Localization:
Secreted. Secreted, extracellular space. Cell membrane ; Single-pass type I membrane protein . Exists both as a membrane-bound form and as soluble form in serum and in the extracellular matrix.
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Tissue Expression:
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Reference Citation({{totalcount}})
Catalog: YP1161
Size
Price
Status
Qty.
200μL
$600.00
In stock
0
100μL
$340.00
In stock
0
50μL
$190.00
In stock
0
Add to cart
Collected
Collect
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