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Rabphilin-3A (Phospho Ser237) Rabbit pAb

-YP0891

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Catalog: YP0891
Size
Price
Status
Qty.
200μL
$600.00
In stock

0

100μL
$340.00
In stock

0

50μL
$190.00
In stock

0

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Main Information
Target

Rabphilin 3A Phospho Ser237

Host Species

Rabbit

Reactivity

Human, Mouse, Rat

Applications

WB, IHC, IF, ELISA

MW

75kD (Observed)

Conjugate/Modification


Phospho

Detailed Information
Recommended Dilution Ratio
WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:10000; Not yet tested in other applications.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
Phospho-Rabphilin-3A (S237) Polyclonal Antibody detects endogenous levels of Rabphilin-3A protein only when phosphorylated at S237.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):RAsEA
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
75kD
Modification
Phospho
Clonality
Polyclonal
Isotype
IgG
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Rabphilin-3A (Phospho Ser237) Rabbit pAb
YP0891

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ELISA Kits
Total Rabphilin 3A Cell-Based Colorimetric ELISA Kit
KA4259C

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Antigen&Target Information
Immunogen:
The antiserum was produced against synthesized peptide derived from human Rabphilin 3A around the phosphorylation site of Ser237. AA range:203-252
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Specificity:
Phospho-Rabphilin-3A (S237) Polyclonal Antibody detects endogenous levels of Rabphilin-3A protein only when phosphorylated at S237.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):RAsEA
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Gene Name:
RPH3A
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Protein Name:
Rabphilin-3A
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Other Name:
RPH3A ;
KIAA0985 ;
Rabphilin-3A ;
Exophilin-1
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Database Link:
Organism Gene ID SwissProt
Human 22895; Q9Y2J0;
Mouse 19894; P47708;
Rat 171039; P47709;
Background:
Exocytosis of neurotransmitters and hormones is fundamental to synaptic neurotransmission and cell-cell communication. RAB3A (MIM 179390) is a small G protein that is thought to act at late stages of exocytosis, and RPH3A is a RAB3A effector (Lin et al., 2007 [PubMed 17149709]).[supplied by OMIM, Jul 2008],
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Function:
Function:Protein transport. Probably involved with Ras-related protein Rab-3A in synaptic vesicle traffic and/or synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal.,similarity:Contains 1 FYVE-type zinc finger.,similarity:Contains 1 RabBD (Rab-binding) domain.,similarity:Contains 2 C2 domains.,
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Cellular Localization:
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane . Cell projection, dendritic spine . Cell junction, synapse, postsynaptic cell membrane . Membrane ; Peripheral membrane protein .
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Tissue Expression:
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Catalog: YP0891
Size
Price
Status
Qty.
200μL
$600.00
In stock

0

100μL
$340.00
In stock

0

50μL
$190.00
In stock

0

Add to cart

Collected

Collect

Customized Service

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