Catalog: YP0837
Size
Price
Status
Qty.
200μL
$600.00
In stock
0
100μL
$340.00
In stock
0
50μL
$190.00
In stock
0
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Collected
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Main Information
Target
UBF-1 Phospho Ser484
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, IHC, IF, ELISA
MW
85kD (Observed)
Conjugate/Modification
Phospho
Detailed Information
Recommended Dilution Ratio
WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:5000; IF 1:50-200
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
Phospho-UBF (S484) Polyclonal Antibody detects endogenous levels of UBF protein only when phosphorylated at S484.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):PEsPK
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
85kD
Modification
Phospho
Clonality
Polyclonal
Isotype
IgG
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UBF-1 Rabbit pAb
YT4804
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UBF-1 Rabbit pAb
YT4803
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Primary Antibodies
UBF-1 (Phospho Ser484) Rabbit pAb
YP0837
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ELISA Kits
Total UBF-1 Cell-Based Colorimetric ELISA Kit
KA3548C
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Antigen&Target Information
Immunogen:
The antiserum was produced against synthesized peptide derived from human UBF around the phosphorylation site of Ser484. AA range:451-500
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Specificity:
Phospho-UBF (S484) Polyclonal Antibody detects endogenous levels of UBF protein only when phosphorylated at S484.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):PEsPK
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Gene Name:
UBTF
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Protein Name:
Nucleolar transcription factor 1
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Other Name:
UBTF ;
UBF ;
UBF1 ;
Nucleolar transcription factor 1 ;
Autoantigen NOR-90 ;
Upstream-binding factor 1 ;
UBF-1
UBF ;
UBF1 ;
Nucleolar transcription factor 1 ;
Autoantigen NOR-90 ;
Upstream-binding factor 1 ;
UBF-1
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Background:
This gene encodes a member of the HMG-box DNA-binding protein family. The encoded protein plays a critical role in ribosomal RNA transcription as a key component of the pre-initiation complex, mediating the recruitment of RNA polymerase I to rDNA promoter regions. The encoded protein may also play important roles in chromatin remodeling and pre-rRNA processing, and its activity is regulated by both phosphorylation and acetylation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Pseudogenes of this gene are located on the short arm of chromosomes 3, 11 and X and the long arm of chromosome 11. [provided by RefSeq, Aug 2011],
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Function:
Function:Recognizes the ribosomal RNA gene promoter and activates transcription mediated by RNA polymerase I through cooperative interactions with the species-specific factor SL1. It binds specifically to the upstream control element.,PTM:Phosphorylated and activated by PIK3CA.,similarity:Contains 6 HMG box DNA-binding domains.,subunit:Homodimer. Binds to IRS1 and PIK3CA.,
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Cellular Localization:
Nucleus, nucleolus .
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Tissue Expression:
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Reference Citation({{totalcount}})
Catalog: YP0837
Size
Price
Status
Qty.
200μL
$600.00
In stock
0
100μL
$340.00
In stock
0
50μL
$190.00
In stock
0
Add to cart
Collected
Collect
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