The antiserum was produced against synthesized peptide derived from human TISB around the phosphorylation site of Ser92. AA range:58-107

Phospho-TIS11B (S92) Polyclonal Antibody detects endogenous levels of TIS11B protein only when phosphorylated at S92.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):SFsEG

ZFP36L1

Zinc finger protein 36 C3H1 type-like 1

ZFP36L1 ;
BERG36 ;
BRF1 ;
ERF1 ;
RNF162B ;
TIS11B ;
Zinc finger protein 36 ;
C3H1 type-like 1 ;
Butyrate response factor 1 ;
EGF-response factor 1 ;
ERF-1 ;
Protein TIS11B

This gene is a member of the TIS11 family of early response genes, which are induced by various agonists such as the phorbol ester TPA and the polypeptide mitogen EGF. This gene is well conserved across species and has a promoter that contains motifs seen in other early-response genes. The encoded protein contains a distinguishing putative zinc finger domain with a repeating cys-his motif. This putative nuclear transcription factor most likely functions in regulating the response to growth factors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011],

Function:Probable regulatory protein involved in regulating the response to growth factors.,similarity:Contains 2 C3H1-type zinc fingers.,

Nucleus . Cytoplasm . Cytoplasmic granule . Cytoplasm, P-body . Shuttles between the nucleus and the cytoplasm in a XPO1/CRM1-dependent manner (By similarity). Component of cytoplasmic stress granules (PubMed:15967811). Localizes in processing bodies (PBs) (PubMed:17369404). .

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