The specific immunogen used to produce this antibody is proprietary information.

Endogenous

RRM1 RR1

Ribonucleoside-diphosphate reductase large subunit (Ribonucleoside-diphosphate reductase subunit M1) (Ribonucleotide reductase large subunit)

CTNNB1 ;
CTNNB ;
OK/SW-cl.35 ;
Catenin beta-1 ;
Beta-catenin

This gene encodes the large and catalytic subunit of ribonucleotide reductase, an enzyme essential for the conversion of ribonucleotides into deoxyribonucleotides. A pool of available deoxyribonucleotides is important for DNA replication during S phase of the cell cycle as well as multiple DNA repair processes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

Cytoplasm

>>Rap1 signaling pathway ;
>>Wnt signaling pathway ;
>>Hippo signaling pathway ;
>>Focal adhesion ;
>>Adherens junction ;
>>Signaling pathways regulating pluripotency of stem cells ;
>>Leukocyte transendothelial migration ;
>>Melanogenesis ;
>>Thyroid hormone signaling pathway ;
>>Cushing syndrome ;
>>Alcoholic liver disease ;
>>Alzheimer disease ;
>>Pathways of neurodegeneration - multiple diseases ;
>>Bacterial invasion of epithelial cells ;
>>Salmonella infection ;
>>Hepatitis C ;
>>Human cytomegalovirus infection ;
>>Human papillomavirus infection ;
>>Kaposi sarcoma-associated herpesvirus infection ;
>>Pathways in cancer ;
>>Proteoglycans in cancer ;
>>Colorectal cancer ;
>>Endometrial cancer ;
>>Prostate cancer ;
>>Thyroid cancer ;
>>Basal cell carcinoma ;
>>Breast cancer ;
>>Hepatocellular carcinoma ;
>>Gastric cancer ;
>>Arrhythmogenic right ventricular cardiomyopathy ;
>>Fluid shear stress and atherosclerosis