Catalog: YV0009
Size
Price
Status
Qty.
100mg
$7,800.00
1 week
0
50mg
$5,600.00
1 week
0
25mg
$3,600.00
1 week
0
5mg
$1,100.00
1 week
0
1mg
$300.00
1 week
0
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Main Information
Target
IgG
Host Species
Rabbit
Applications
In vivo
Detailed Information
Formulation
0.01M PBS, pH 7.4.
Purification
Protein A/G purified from cell culture supernatant.
Purity
Endotoxin level <1 EU/mg. Purity>95% as determined by SDS-PAGE.
Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Concentration
Lot depended
Clonality
Monoclonal
Isotype
IgG
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Antigen&Target Information
Background:
This gene encodes a cell surface membrane protein of the immunoglobulin superfamily.This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice , expression ofThis gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient forThis gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest thatThis gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. [provided by RefSeq , Jul 2008]
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Function:
developmental stage:Induced at programmed cell death. ,Disease:Genetic variation in PDCD1 is associated with susceptibility to systemic lupus erythematosus type 2 (SLEB2) [MIM:605218]. Systemic lupus erythematosus is a chronic , inflammatory and often febrile multisystemic disorder of connective tissue. It affects principally the skin , joints , kidneys and serosal membranes. It is thought to represent a failure of the regulatory mechanisms of the autoimmune system. ,Possible cell death inducer , in association with other factors. ,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain. ,subunit:Monomer. ,
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Cellular Localization:
Cell membrane ; Single-pass type I membrane protein.
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Research Areas:
For research use only.
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Reference Citation({{totalcount}})
Catalog: YV0009
Size
Price
Status
Qty.
100mg
$7,800.00
1 week
0
50mg
$5,600.00
1 week
0
25mg
$3,600.00
1 week
0
5mg
$1,100.00
1 week
0
1mg
$300.00
1 week
0
Add to cart
Collected
Collect
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