Catalog: YN1700
Size
Price
Status
Qty.
200μL
$450.00
4 weeks
0
100μL
$280.00
4 weeks
0
40μL
$150.00
4 weeks
0
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Collected
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Main Information
Target
Ctip2
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
WB, ELISA
MW
98kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-2000; ELISA 1:5000-20000
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
BC11B Polyclonal Antibody detects endogenous levels of protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year (Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
98kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from human protein . at AA range: 570-650
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Specificity:
BC11B Polyclonal Antibody detects endogenous levels of protein.
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Gene Name:
BCL11B CTIP2 RIT1
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Protein Name:
B-cell lymphoma/leukemia 11B (BCL-11B) (B-cell CLL/lymphoma 11B) (COUP-TF-interacting protein 2) (Radiation-induced tumor suppressor gene 1 protein) (hRit1)
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Background:
B-cell CLL/lymphoma 11B (BCL11B) Homo sapiens This gene encodes a C2H2-type zinc finger protein and is closely related to BCL11A , a gene whose translocation may be associated with B-cell malignancies. Although the specific function of this gene has not been determined , the encoded protein is known to be a transcriptional repressor , and is regulated by the NURD nucleosome remodeling and histone deacetylase complex. Four alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq , Aug 2013] ,
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Function:
Function:Tumor-suppressor protein involved in T-cell lymphomas. May function on the P53-signaling pathway. May be a key regulator of both differentiation and survival during thymocyte development. Repress transcription through direct , TFCOUP2-independent binding to a GC-rich response element. ,similarity:Contains 6 C2H2-type zinc fingers. ,subunit:Interacts with TFCOUP1 , SIRT1 , ARP1 and EAR2. ,tissue specificity:Highly expressed in brain and in malignant T-cell lines derived from patients with adult T-cell leukemia/lymphoma. ,
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Cellular Localization:
Nucleus .
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Tissue Expression:
Research Areas:
>>Transcriptional misregulation in cancer
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Reference Citation({{totalcount}})
Catalog: YN1700
Size
Price
Status
Qty.
200μL
$450.00
4 weeks
0
100μL
$280.00
4 weeks
0
40μL
$150.00
4 weeks
0
Add to cart
Collected
Collect
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