Catalog: YT5028
Size
Price
Status
Qty.
200μL
$450.00
4 weeks
0
100μL
$280.00
4 weeks
0
40μL
$150.00
4 weeks
0
Add to cart
Collected
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Main Information
Target
EEA1
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
WB, ELISA
MW
162kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-1:2000; ELISA 1:20000; Not yet tested in other applications.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
EEA1 Polyclonal Antibody detects endogenous levels of EEA1 protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year (Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
162kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
The antiserum was produced against synthesized peptide derived from human EEA1. AA range:205-254
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Specificity:
EEA1 Polyclonal Antibody detects endogenous levels of EEA1 protein.
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Gene Name:
EEA1
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Protein Name:
Early endosome antigen 1
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Other Name:
EEA1 ;
ZFYVE2 ;
Early endosome antigen 1 ;
Endosome-associated protein p162 ;
Zinc finger FYVE domain-containing protein 2
ZFYVE2 ;
Early endosome antigen 1 ;
Endosome-associated protein p162 ;
Zinc finger FYVE domain-containing protein 2
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Background:
disease:Antibodies against EEA1 are found in sera from patients with subacute cutaneous lupus erythematosus and other autoimmune diseases. ,domain:The FYVE-type zinc finger domain mediates interactions with phosphatidylinositol 3-phosphate. ,function:Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in endosomal trafficking. ,similarity:Contains 1 C2H2-type zinc finger. ,similarity:Contains 1 FYVE-type zinc finger. ,subunit:Homodimer. Binds STX6. Binds RAB5A , RAB5B , RAB5C and RAB22A that have been activated by GTP-binding. ,
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Function:
Disease:Antibodies against EEA1 are found in sera from patients with subacute cutaneous lupus erythematosus and other autoimmune diseases. ,Domain:The FYVE-type zinc finger domain mediates interactions with phosphatidylinositol 3-phosphate. ,Function:Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in endosomal trafficking. ,similarity:Contains 1 C2H2-type zinc finger. ,similarity:Contains 1 FYVE-type zinc finger. ,subunit:Homodimer. Binds STX6. Binds RAB5A , RAB5B , RAB5C and RAB22A that have been activated by GTP-binding. ,
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Cellular Localization:
Cytoplasm. Early endosome membrane; Peripheral membrane protein.
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Tissue Expression:
Research Areas:
>>Endocytosis ;
>>Phagosome ;
>>Tuberculosis
>>Phagosome ;
>>Tuberculosis
show all
Signaling Pathway
Reference Citation({{totalcount}})
Catalog: YT5028
Size
Price
Status
Qty.
200μL
$450.00
4 weeks
0
100μL
$280.00
4 weeks
0
40μL
$150.00
4 weeks
0
Add to cart
Collected
Collect
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