GDI-2 Polyclonal Antibody

    • Catalog No.:YT5317
    • Applications:WB,IHC-p,IF(paraffin section),ELISA
    • Reactivity:Human,Mouse,Rat
      • Gene Name:
      • GDI2
      • Protein Name:
      • Rab GDP dissociation inhibitor beta
      • Human Gene Id:
      • 2665
      • Human Swiss Prot No:
      • P50395
      • Mouse Swiss Prot No:
      • Q61598
      • Immunogen:
      • Synthesized peptide derived from the C-terminal region of human GDI-2.
      • Specificity:
      • GDI-2 Polyclonal Antibody detects endogenous levels of GDI-2 protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Rabbit
      • Dilution:
      • Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -20°C/1 year
      • Other Name:
      • GDI2; RABGDIB; Rab GDP dissociation inhibitor beta; Rab GDI beta; Guanosine diphosphate dissociation inhibitor 2; GDI-2
      • MolecularWeight(Da):
      • 50663
      • Observed Band(KD):
      • 50
      • Background:
      • GDP dissociation inhibitor 2(GDI2) Homo sapiens GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI2 is ubiquitously expressed. The GDI2 gene contains many repetitive elements indicating that it may be prone to inversion/deletion rearrangements. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008],
      • Function:
      • function:Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them.,similarity:Belongs to the Rab GDI family.,tissue specificity:Ubiquitous.,
      • Subcellular Location:
      • intracellular,cytoplasm,Golgi apparatus,cytosol,focal adhesion,membrane,vesicle,myelin sheath,extracellular exosome,
      • Expression:
      • Bone marrow,Brain,Hippocampus,Pancreas,Placenta,
      • Products Images
      • Western Blot analysis of A549, HT29, K562, mouse kidney, mouse lung cells using GDI-2 Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
      • Immunohistochemical analysis of paraffin-embedded rat-brain, antibody was diluted at 1:100
      • Immunohistochemical analysis of paraffin-embedded rat-brain, antibody was diluted at 1:100
      • Immunohistochemical analysis of paraffin-embedded rat-brain, antibody was diluted at 1:100
      • Immunohistochemical analysis of paraffin-embedded mouse-brain, antibody was diluted at 1:100