• Target：
• GNAI3

• Fields：
• >>Rap1 signaling pathway;>>cGMP-PKG signaling pathway;>>cAMP signaling pathway;>>Chemokine signaling pathway;>>Sphingolipid signaling pathway;>>Adrenergic signaling in cardiomyocytes;>>Axon guidance;>>Apelin signaling pathway;>>Gap junction;>>Platelet activation;>>Leukocyte transendothelial migration;>>Circadian entrainment;>>Retrograde endocannabinoid signaling;>>Glutamatergic synapse;>>Cholinergic synapse;>>Serotonergic synapse;>>GABAergic synapse;>>Dopaminergic synapse;>>Long-term depression;>>Progesterone-mediated oocyte maturation;>>Estrogen signaling pathway;>>Melanogenesis;>>Oxytocin signaling pathway;>>Regulation of lipolysis in adipocytes;>>Renin secretion;>>Relaxin signaling pathway;>>Parathyroid hormone synthesis, secretion and action;>>Cushing syndrome;>>Growth hormone synthesis, secretion and action;>>Gastric acid secretion;>>Parkinson disease;>>Cocaine addiction;>>Morphine addiction;>>Alcoholism;>>Pertussis;>>Chagas disease;>>Toxoplasmosis;>>Human cytomegalovirus infectio

• Gene Name：
• GNAI3

• Protein Name：
• Guanine nucleotide-binding protein G(k) subunit alpha

• Human Gene Id：
• 2773

• Human Swiss Prot No：
• P08754

• Mouse Gene Id：
• 14679

• Mouse Swiss Prot No：
• Q9DC51

• Rat Gene Id：
• 25643

• Rat Swiss Prot No：
• P08753

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human GNAI3. AA range:31-80

• Specificity：
• Gα i-3 Polyclonal Antibody detects endogenous levels of Gα i-3 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• GNAI3;Guanine nucleotide-binding protein G(k) subunit alpha;G(i) alpha-3

• Observed Band(KD)：
• 41kD

• Background：
• Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling pathways. G proteins are composed of 3 units: alpha, beta and gamma. This gene encodes an alpha subunit and belongs to the G-alpha family. Mutation in this gene, resulting in a gly40-to-arg substitution, is associated with auriculocondylar syndrome, and shown to affect downstream targets in the G protein-coupled endothelin receptor pathway. [provided by RefSeq, Jun 2012],

• Function：
• function:Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G(k) is the stimulatory G protein of receptor-regulated K(+) channels.,similarity:Belongs to the G-alpha family. G(i/o/t/z) subfamily.,subunit:G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site. Interacts with GPSM1.,

• Subcellular Location：
• Cytoplasm . Cell membrane ; Lipid-anchor . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Localizes in the centrosomes of interphase and mitotic cells. Detected at the cleavage furrow and/or the midbody. .

• Expression：
• Liver,

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