• Target：
• Eps8L1

• Gene Name：
• EPS8L1

• Protein Name：
• Epidermal growth factor receptor kinase substrate 8-like protein 1

• Human Gene Id：
• 54869

• Human Swiss Prot No：
• Q8TE68

• Mouse Gene Id：
• 67425

• Mouse Swiss Prot No：
• Q8R5F8

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human ES8L1. AA range:411-460

• Specificity：
• Eps8L1 Polyclonal Antibody detects endogenous levels of Eps8L1 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• EPS8L1;DRC3;EPS8R1;PP10566;Epidermal growth factor receptor kinase substrate 8-like protein 1;EPS8-like protein 1;Epidermal growth factor receptor pathway substrate 8-related protein 1;EPS8-related protein 1

• Observed Band(KD)：
• 80kD

• Background：
• This gene encodes a protein that is related to epidermal growth factor receptor pathway substrate 8 (EPS8), a substrate for the epidermal growth factor receptor. The function of this protein is unknown. At least two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

• Function：
• function:Stimulates guanine exchange activity of SOS1. May play a role in membrane ruffling and remodeling of the actin cytoskeleton.,similarity:Belongs to the EPS8 family.,similarity:Contains 1 SH3 domain.,subunit:Interacts with ABI1. Part of a complex that contains SOS1, ABI1 and EPS8L2. Associates with F-actin.,tissue specificity:Detected in placenta.,

• Subcellular Location：
• Cytoplasm .

• Expression：
• Detected in placenta.

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