• Target：
• ARHGAP1

• Gene Name：
• ARHGAP1

• Protein Name：
• Rho GTPase-activating protein 1

• Human Gene Id：
• 392

• Human Swiss Prot No：
• Q07960

• Mouse Gene Id：
• 228359

• Mouse Swiss Prot No：
• Q5FWK3

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human RHG1. AA range:189-238

• Specificity：
• ARHGAP1 Polyclonal Antibody detects endogenous levels of ARHGAP1 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• ARHGAP1;CDC42GAP;RHOGAP1;Rho GTPase-activating protein 1;CDC42 GTPase-activating protein;GTPase-activating protein rhoOGAP;Rho-related small GTPase protein activator;Rho-type GTPase-activating protein 1;p50-RhoGAP

• Observed Band(KD)：
• 50kD

• Background：
• This gene encodes a member of a large family of proteins that activate Rho-type guanosine triphosphate (GTP) metabolizing enzymes. The encoded protein contains a SRC homology 3 domain and interacts with Bcl-2-associated protein family members. [provided by RefSeq, Aug 2012],

• Function：
• function:GTPase activator for the Rho, Rac and Cdc42 proteins, converting them to the putatively inactive GDP-bound state. Cdc42 seems to be the preferred substrate.,similarity:Contains 1 CRAL-TRIO domain.,similarity:Contains 1 Rho-GAP domain.,subunit:Found in a complex with XPO7, EIF4A1, ARHGAP1, VPS26A, VPS29, VPS35 and SFN. Interacts with BNIPL.,tissue specificity:Ubiquitous.,

• Subcellular Location：
• Cytoplasm.

• Expression：
• Ubiquitous.

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