N-Cadherin (ABT156R) rabbit mAb

  • Catalog No.：YM8015
  • Applications：WB; IHC; ELISA
  • Reactivity：Human; Mouse; (predicted: Rat)
    • Target：
    • N-Cadherin
    • Fields：
    • >>Cell adhesion molecules;>>Arrhythmogenic right ventricular cardiomyopathy
    • Gene Name：
    • CDH2;CDHN;NCAD
    • Protein Name：
    • Cadherin-2 (CDw325) (Neural cadherin) (N-cadherin) (CD antigen CD325)
    • Human Gene Id：
    • 1000
    • Human Swiss Prot No：
    • P19022
    • Immunogen：
    • Synthesized peptide derived from human N-Cadherin AA range:200-400
    • Specificity：
    • This antibody detects endogenous levels of N-Cadherin
    • Formulation：
    • PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
    • Source：
    • Monoclonal, Rabbit IgG1, Kappa
    • Dilution：
    • IHC 1:100-500, WB 1:500-1000, ELISA 1:5000-20000
    • Purification：
    • Recombinant Expression and Affinity purified
    • Storage Stability：
    • -15°C to -25°C/1 year(Do not lower than -25°C)
    • Other Name：
    • Cadherin-2;CDw325;Neural cadherin (N-cadherin;CD325;CDH2
    • Molecular Weight(Da)：
    • 100kD
    • Background：
    • This gene encodes a classical cadherin and member of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein is proteolytically processed to generate a calcium-dependent cell adhesion molecule and glycoprotein. This protein plays a role in the establishment of left-right asymmetry, development of the nervous system and the formation of cartilage and bone. [provided by RefSeq, Nov 2015],
    • Function：
    • function:Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH2 may be involved in neuronal recognition mechanism.,similarity:Contains 5 cadherin domains.,subunit:Interacts with CDCP1.,
    • Subcellular Location：
    • Cell membrane ; Single-pass type I membrane protein . Cell membrane, sarcolemma . Cell junction . Cell surface . Colocalizes with TMEM65 at the intercalated disk in cardiomyocytes. Colocalizes with OBSCN at the intercalated disk and at sarcolemma in cardiomyocytes. .
    • Expression：
    • Brain,Epithelium,Liver,

    Attributes

    • Code：
    • YM8015
    • Size
    • 40μL / 100μL / 200μL
    • Price$：
    • 190 / 340 / 600
    • Delivery：
    • 2024-06-14
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