Oct-2 (PT0120R) rabbit mAb

  • Catalog No.：YM7177
  • Applications：IHC;WB; ELISA
  • Reactivity：Human; Mouse;
    • Target：
    • Oct-2
    • Fields：
    • >>Herpes simplex virus 1 infection;>>Lipid and atherosclerosis
    • Gene Name：
    • POU2F2
    • Protein Name：
    • Oct-2
    • Human Gene Id：
    • 5452
    • Human Swiss Prot No：
    • P09086
    • Immunogen：
    • Synthesized peptide derived from human Oct-2 AA range:250-350
    • Specificity：
    • This antibody detects endogenous levels of Oct-2
    • Formulation：
    • PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
    • Source：
    • Monoclonal, Rabbit IgG1, Kappa
    • Dilution：
    • IHC 1:100-500, WB 1:500-1000, ELISA 1:5000-20000
    • Purification：
    • Recombinant Expression and Affinity purified
    • Storage Stability：
    • -15°C to -25°C/1 year(Do not lower than -25°C)
    • Other Name：
    • class 2;Lymphoid restricted immunoglobulin octamer binding protein;Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2;NF A2;Oct 2;Oct-2;Octamer binding transcription factor 2;Octamer-binding protein 2;Octamer-binding transcription factor 2;OTF-2;OTF2;PO2F2_HUMAN;POU domain;POU domain class 2 transcription factor 2;POU2F2;transcription factor 2
    • Molecular Weight(Da)：
    • 51kD
    • Background：
    • The protein encoded by this gene is a homeobox-containing transcription factor of the POU domain family. The encoded protein binds the octamer sequence 5'-ATTTGCAT-3', a common transcription factor binding site in immunoglobulin gene promoters. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011],
    • Function：
    • function:Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3'). Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. Modulates transcription transactivation by NR3C1, AR and PGR. Isoform 5 activates the U2 small nuclear RNA (snRNA) promoter.,similarity:Belongs to the POU transcription factor family. Class-2 subfamily.,similarity:Contains 1 homeobox DNA-binding domain.,similarity:Contains 1 POU-specific domain.,subunit:Interacts with NR3C1, AR and PGR.,tissue specificity:Isoform 3 is B-cell specific. Isoform 5 is expressed in B-cells and the immunoglobulin-expressing T-cell line Molt-4, but not in the T-cell line BW 5147.,
    • Subcellular Location：
    • Nuclear
    • Expression：
    • Isoform 3 is B-cell specific. Isoform 5 is expressed in B-cells and the immunoglobulin-expressing T-cell line MOLT-4, but not in the T-cell line BW5147.

    Attributes

    • Code：
    • YM7177
    • Size
    • 40μL / 100μL / 200μL
    • Price$：
    • 190 / 340 / 600
    • Delivery：
    • 2024-05-16
    Order

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