Phospho PLCG2 (Y753) Cell-Based Colorimetric ELISA Kit

  • 货号:KA1215C
  • 应用:ELISA
  • 种属:Human;Mouse;Rat
    • 基因名称:
    • PLCG2
    • Human Gene Id:
    • 5336
    • Human Swiss Prot No:
    • P16885
    • Mouse Swiss Prot No:
    • Q8CIH5
    • 储存:
    • 2-8°C/6 months
    • 其他名称:
    • 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (EC 3.1.4.11) (Phosphoinositide phospholipase C-gamma-2) (Phospholipase C-IV) (PLC-IV) (Phospholipase C-gamma-2) (PLC-gamma-2)
    • 检测方法:
    • Colorimetric
    • 背景:
    • catalytic activity:1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H(2)O = 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol.,cofactor:Calcium.,function:The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. It is a crucial enzyme in transmembrane signaling.,PTM:Phosphorylated on tyrosine residues; upon ligand-induced activation of a variety of growth factor receptors and immune system receptors. Increases phospholipase activity.,similarity:Contains 1 C2 domain.,similarity:Contains 1 PH domain.,similarity:Contains 1 PI-PLC X-box domain.,similarity:Contains 1 PI-PLC Y-box domain.,similarity:Contains 1 SH3 domain.,similarity:Contains 2 SH2 domains.,
    • 功能:
    • cell activation, response to molecule of bacterial origin, activation of immune response, cell activation during immune response, lymphocyte activation during immune response, B cell activation during immune response, mature B cell differentiation during immune response, follicular B cell differentiation, mature B cell differentiation, leukocyte activation during immune response, immune response-activating cell surface receptor signaling pathway, immune system development, leukocyte differentiation, positive regulation of immune system process, immune response-activating signal transduction, immune response-regulating signal transduction, immune response-regulating cell surface receptor signaling pathway, inositol metabolic process, inositol biosynthetic process, phospholipid metabolic process, cellular ion homeostasis, cellular calcium ion homeostasis, cellular metal ion homeostasis, im