Rab 40B Polyclonal Antibody

    • Catalog No.:YT3934
    • Applications:WB;IHC;IF;ELISA
    • Reactivity:Human;Rat;Mouse;
      • Target:
      • Rab 40B
      • Gene Name:
      • RAB40B
      • Protein Name:
      • Ras-related protein Rab-40B
      • Human Swiss Prot No:
      • Q12829
      • Mouse Swiss Prot No:
      • Q8VHP8
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human RAB40B. AA range:229-278
      • Specificity:
      • Rab 40B Polyclonal Antibody detects endogenous levels of Rab 40B protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500 - 1:2000. ELISA: 1:40000.. IF 1:50-200
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • RAB40B;SEC4L;Ras-related protein Rab-40B;SOCS box-containing protein RAR;Protein Rar
      • Observed Band(KD):
      • 34kD
      • Background:
      • The protein encoded by this gene has similarity to a yeast protein which suggests a role of the gene product in regulating secretory vesicles. [provided by RefSeq, Jul 2008],
      • Function:
      • domain:The SOCS box domain mediates the interaction with the Elongin BC complex, an adapter module in different E3 ubiquitin ligase complexes.,function:May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.,pathway:Protein modification; protein ubiquitination.,similarity:Belongs to the small GTPase superfamily. Rab family.,similarity:Contains 1 SOCS box domain.,
      • Subcellular Location:
      • Cell membrane ; Lipid-anchor ; Cytoplasmic side .
      • Expression:
      • Brain,Hippocampus,
      • Products Images
      • Western Blot analysis of Jurkat cells using Rab 40B Polyclonal Antibody
      • Immunohistochemical analysis of paraffin-embedded Human brain. Antibody was diluted at 1:100(4° overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by immunogen peptide.
      • Western blot analysis of lysates from Jurkat cells, using RAB40B Antibody. The lane on the right is blocked with the synthesized peptide.