FASTKD3 Polyclonal Antibody

    • Catalog No.:YT1682
    • Applications:WB;IHC;IF;ELISA
    • Reactivity:Human;Rat;Mouse;
      • Target:
      • FASTKD3
      • Gene Name:
      • FASTKD3
      • Protein Name:
      • FAST kinase domain-containing protein 3
      • Human Swiss Prot No:
      • Q14CZ7
      • Mouse Swiss Prot No:
      • Q8BSN9
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human FAKD3. AA range:121-170
      • Specificity:
      • FASTKD3 Polyclonal Antibody detects endogenous levels of FASTKD3 protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • FASTKD3;FAST kinase domain-containing protein 3
      • Observed Band(KD):
      • 75kD
      • Background:
      • This gene encodes a member of a small family of Fas-activated serine/threonine kinase domain (FASTKD) containing proteins that share an amino terminal mitochondrial targeting domain and multiple carboxy terminal FAST domains as well as a putative RNA-binding RAP domain. The members of this family are ubiquitously expressed and are generally most abundant in mitochondria-enriched tissues such as heart, skeletal muscle and brown-adipose tissue. Some members of this protein family may play a role in apoptosis. The protein encoded by this gene interacts with components of the mitochondrial respiratory and translation networks. A pseudogene of this gene is also present on chromosome 5. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013],
      • Function:
      • similarity:Belongs to the FAST kinase family.,similarity:Contains 1 RAP domain.,
      • Subcellular Location:
      • Mitochondrion .
      • Expression:
      • Expression detected in spleen, thymus, testis, ovary, colon, heart, smooth muscle, kidney, brain, lung, liver and white adipose tissue with highest expression in liver and thyroid.
      • Products Images
      • Western Blot analysis of various cells using FASTKD3 Polyclonal Antibody
      • Western blot analysis of lysates from HepG2 cells, using FAKD3 Antibody. The lane on the right is blocked with the synthesized peptide.