CD83 Polyclonal Antibody

    • Catalog No.:YT0779
    • Applications:WB;IHC;IF;ELISA
    • Reactivity:Human;Rat;Mouse;
      • Target:
      • CD83
      • Gene Name:
      • CD83
      • Protein Name:
      • CD83 antigen
      • Human Gene Id:
      • 9308
      • Human Swiss Prot No:
      • Q01151
      • Mouse Swiss Prot No:
      • O88324
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human CD83. AA range:101-150
      • Specificity:
      • CD83 Polyclonal Antibody detects endogenous levels of CD83 protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • CD83;CD83 antigen;hCD83;B-cell activation protein;Cell surface protein HB15;CD antigen CD83
      • Observed Band(KD):
      • 23kD
      • Background:
      • The protein encoded by this gene is a single-pass type I membrane protein and member of the immunoglobulin superfamily of receptors. The encoded protein may be involved in the regulation of antigen presentation. A soluble form of this protein can bind to dendritic cells and inhibit their maturation. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011],
      • Function:
      • function:May play a significant role in antigen presentation or the cellular interactions that follow lymphocyte activation.,online information:CD83 antigen,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,subunit:Monomer.,tissue specificity:Expressed by activated lymphocytes, Langerhans cells and interdigitating reticulum cells.,
      • Subcellular Location:
      • Membrane; Single-pass type I membrane protein.
      • Expression:
      • Expressed by activated lymphocytes, Langerhans cells and interdigitating reticulum cells.
      • Products Images
      • Immunohistochemical analysis of paraffin-embedded Human kidney. 1, Antibody was diluted at 1:400(4° overnight). 2, High-pressure and temperature EDTA, pH8.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min).
      • Immunohistochemical analysis of paraffin-embedded Human stomach. 1, Antibody was diluted at 1:400(4° overnight). 2, High-pressure and temperature EDTA, pH8.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min).
      • Immunohistochemistry analysis of paraffin-embedded human lung carcinoma, using CD83 Antibody. The picture on the right is blocked with the synthesized peptide.
      • Western blot analysis of lysates from HepG2 cells, HUVEC cells, HeLa cells, and Jurkat cells, using CD83 Antibody. The lane on the right is blocked with the synthesized peptide.