TBB1 Polyclonal Antibody

  • Catalog No.:YN1906
  • Applications:WB;ELISA
  • Reactivity:Human;Mouse
    • Target:
    • Tubulin β
    • Fields:
    • >>Phagosome;>>Gap junction;>>Alzheimer disease;>>Parkinson disease;>>Amyotrophic lateral sclerosis;>>Huntington disease;>>Prion disease;>>Pathways of neurodegeneration - multiple diseases;>>Pathogenic Escherichia coli infection;>>Salmonella infection
    • Gene Name:
    • TUBB1
    • Protein Name:
    • Tubulin beta-1 chain
    • Human Swiss Prot No:
    • Q9H4B7
    • Mouse Swiss Prot No:
    • A2AQ07
    • Immunogen:
    • Synthesized peptide derived from part region of human protein AA range: 257-307
    • Specificity:
    • TBB1 Polyclonal Antibody detects endogenous levels of protein.
    • Formulation:
    • Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
    • Source:
    • Polyclonal, Rabbit,IgG
    • Dilution:
    • WB 1:500-2000 ELISA 1:5000-20000
    • Purification:
    • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    • Concentration:
    • 1 mg/ml
    • Storage Stability:
    • -15°C to -25°C/1 year(Do not lower than -25°C)
    • Observed Band(KD):
    • 49kD
    • Background:
    • This gene encodes a member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is specifically expressed in platelets and megakaryocytes and may be involved in proplatelet production and platelet release. A mutations in this gene is associated with autosomal dominant macrothrombocytopenia. Two pseudogenes of this gene are found on chromosome Y.[provided by RefSeq, Jul 2010],
    • Function:
    • function:Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain.,similarity:Belongs to the tubulin family.,subunit:Dimer of alpha and beta chains.,
    • Subcellular Location:
    • Cytoplasm, cytoskeleton .
    • Expression:
    • Hematopoietic cell-specific. Major isotype in leukocytes, where it represents 50% of all beta-tubulins.