• Target：
• β-1,3-Gal-TL

• Fields：
• >>Other types of O-glycan biosynthesis

• Gene Name：
• B3GALTL

• Protein Name：
• Beta-1,3-glucosyltransferase

• Human Gene Id：
• 145173

• Human Swiss Prot No：
• Q6Y288

• Mouse Swiss Prot No：
• Q8BHT6

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human B3GALTL. AA range:449-498

• Specificity：
• β-1,3-Gal-TL Polyclonal Antibody detects endogenous levels of β-1,3-Gal-TL protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• B3GALTL;B3GTL;Beta-1;3-glucosyltransferase;Beta3Glc-T;Beta-3-glycosyltransferase-like

• Observed Band(KD)：
• 57kD

• Background：
• The protein encoded by this gene is a beta-1,3-glucosyltransferase that transfers glucose to O-linked fucosylglycans on thrombospondin type-1 repeats (TSRs) of several proteins. The encoded protein is a type II membrane protein. Defects in this gene are a cause of Peters-plus syndrome (PPS).[provided by RefSeq, Mar 2009],

• Function：
• disease:Defects in B3GALTL are the cause of Peters-plus syndrome (PPS) [MIM:261540]. PPS is an autosomal recessive disorder characterized by anterior eye-chamber abnormalities, disproportionate short stature, developmental delay, characteristic craniofacial features, cleft lip and/or palate.,function:O-fucosyltransferase that transfers glucose toward fucose with a beta-1,3 linkage. Specifically glucosylates O-linked fucosylglycan on TSP type-1 domains of proteins, thereby contributing to elongation of O-fucosylglycan.,online information:GlycoGene database,pathway:Protein modification; protein glycosylation.,similarity:Belongs to the glycosyltransferase 31 family.,tissue specificity:Widely expressed, with highest levels in testis and uterus.,

• Subcellular Location：
• Endoplasmic reticulum membrane ; Single-pass type II membrane protein .

• Expression：
• Widely expressed, with highest levels in testis and uterus.

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