TNNI3K Polyclonal Antibody
- Catalog No.:YT4692
- Applications:WB;IHC;IF;ELISA
- Reactivity:Human;Mouse;Rat
- Target:
- TNNI3K
- Gene Name:
- TNNI3K
- Protein Name:
- Serine/threonine-protein kinase TNNI3K
- Human Gene Id:
- 51086
- Human Swiss Prot No:
- Q59H18
- Mouse Gene Id:
- 435766
- Mouse Swiss Prot No:
- Q5GIG6
- Rat Gene Id:
- 295531
- Rat Swiss Prot No:
- Q7TQP6
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human TNNI3K. AA range:301-350
- Specificity:
- TNNI3K Polyclonal Antibody detects endogenous levels of TNNI3K protein.
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500-2000 IHC 1:100 - 1:300. ELISA: 1:10000. IF 1:50-200
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- TNNI3K;CARK;Serine/threonine-protein kinase TNNI3K;Cardiac ankyrin repeat kinase;Cardiac troponin I-interacting kinase;TNNI3-interacting kinase
- Molecular Weight(Da):
- 104kD
- Background:
- This gene encodes a protein that belongs to the MAP kinase kinase kinase (MAPKKK) family of protein kinases. The protein contains ankyrin repeat, protein kinase and serine-rich domains and is thought to play a role in cardiac physiology. [provided by RefSeq, Sep 2012],
- Function:
- catalytic activity:ATP + a protein = ADP + a phosphoprotein.,catalytic activity:GTP + beta-L-fucose 1-phosphate = diphosphate + GDP-L-fucose.,cofactor:Magnesium.,function:Catalyzes the formation of GDP-L-fucose from GTP and L-fucose-1-phosphate. Functions as a salvage pathway to reutilize L-fucose arising from the turnover of glycoproteins and glycolipids.,function:May play a role in cardiac physiology.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 10 ANK repeats.,subcellular location:Expressed at lower levels in the cytoplasm.,subunit:Interacts with TNNI3, ACTC, ACTA1, MYBPC3, AIP, BABP3 and HADHB.,tissue specificity:Expressed in many tissues.,tissue specificity:Highly expressed in both adult and fetal heart.,
- Subcellular Location:
- Nucleus . Cytoplasm . Expressed at lower levels in the cytoplasm.
- Expression:
- Highly expressed in both adult and fetal heart.
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- Antibody-FAQs
- Products Images
- Western blot analysis of Mouse-kidney lysis using TNNI3K antibody. Antibody was diluted at 1:500. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
- Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using TNNI3K Antibody. The picture on the right is blocked with the synthesized peptide.