ALS Polyclonal Antibody

    • Catalog No.：YT0201
    • Applications：WB;ELISA
    • Reactivity：Human;Rat;Mouse;
      • Target：
      • ALS
      • Fields：
      • >>Growth hormone synthesis, secretion and action
      • Gene Name：
      • IGFALS
      • Protein Name：
      • Insulin-like growth factor-binding protein complex acid labile subunit
      • Human Gene Id：
      • 3483
      • Human Swiss Prot No：
      • P35858
      • Mouse Swiss Prot No：
      • P70389
      • Immunogen：
      • The antiserum was produced against synthesized peptide derived from human IGFALS. AA range:303-352
      • Specificity：
      • ALS Polyclonal Antibody detects endogenous levels of ALS protein.
      • Formulation：
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source：
      • Polyclonal, Rabbit,IgG
      • Dilution：
      • WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
      • Purification：
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration：
      • 1 mg/ml
      • Storage Stability：
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name：
      • IGFALS;ALS;Insulin-like growth factor-binding protein complex acid labile subunit;ALS
      • Observed Band(KD)：
      • 66kD
      • Background：
      • The protein encoded by this gene is a serum protein that binds insulin-like growth factors, increasing their half-life and their vascular localization. Production of the encoded protein, which contains twenty leucine-rich repeats, is stimulated by growth hormone. Defects in this gene are a cause of acid-labile subunit deficiency, which maifests itself in a delayed and slow puberty. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Mar 2009],
      • Function：
      • function:Involved in protein-protein interactions that result in protein complexes, receptor-ligand binding or cell adhesion.,similarity:Contains 20 LRR (leucine-rich) repeats.,subunit:Forms a ternary complex of about 140 to 150 kDa with IGF-I or IGF-II and IGFBP-3.,tissue specificity:Plasma.,
      • Subcellular Location：
      • Secreted, extracellular space.
      • Expression：
      • Plasma.
      • Products Images
      • Western Blot analysis of CoLo cells using ALS Polyclonal Antibody
      • Western blot analysis of IGFALS Antibody. The lane on the right is blocked with the IGFALS peptide.
      • Western blot analysis of the lysates from RAW264.7cells using IGFALS antibody.

      Attributes

      • Code：
      • YT0201
      • Size
      • 40μL / 100μL / 200μL
      • Price$：
      • 150 / 280 / 450
      • Delivery：
      • 2024-04-29
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