• Target：
• AIRP

• Fields：
• >>Purine metabolism;>>Pyrimidine metabolism;>>Nicotinate and nicotinamide metabolism;>>Metabolic pathways;>>Nucleotide metabolism

• Gene Name：
• NT5C1B

• Protein Name：
• Cytosolic 5'-nucleotidase 1B

• Human Gene Id：
• 93034

• Human Swiss Prot No：
• Q96P26

• Mouse Swiss Prot No：
• Q91YE9

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human NT5C1B. AA range:171-220

• Specificity：
• AIRP Polyclonal Antibody detects endogenous levels of AIRP protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500-2000 IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• NT5C1B;AIRP;FKSG85;Cytosolic 5'-nucleotidase 1B;cN1B;Autoimmune infertility-related protein;Cytosolic 5'-nucleotidase IB;cN-IB

• Observed Band(KD)：
• 69kD

• Background：
• Cytosolic 5-prime nucleotidases, such as NT5C1B, catalyze production of adenosine, which regulates diverse physiologic processes (Sala-Newby and Newby, 2001 [PubMed 11690631]).[supplied by OMIM, Mar 2008],

• Function：
• catalytic activity:A 5'-ribonucleotide + H(2)O = a ribonucleoside + phosphate.,cofactor:Magnesium.,enzyme regulation:Activated by ADP.,function:Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides. Helps to regulate adenosine levels.,function:Exhibits an oxidoreductive catalytic activity towards retinoids. Most efficient as an NADPH-dependent retinal reductase. Displays high activity toward 9-cis and all-trans-retinol. No steroid dehydrogenase activity detected.,similarity:Belongs to the 5'-nucleotidase type 3 family.,similarity:Belongs to the short-chain dehydrogenases/reductases (SDR) family.,tissue specificity:Expressed in brain, kidney, pancreas and placenta.,tissue specificity:Highly expressed in testis, placenta and pancreas. Detected at lower levels in heart, kidney, liver and lung.,

• Subcellular Location：
• Cytoplasm .

• Expression：
• Highly expressed in testis, placenta and pancreas. Detected at lower levels in heart, kidney, liver and lung.

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