ITB8 Polyclonal Antibody

  • Catalog No.：YN1771
  • Applications：WB;ELISA
  • Reactivity：Human;Rat;Mouse;
    • Target：
    • ITB8
    • Fields：
    • >>PI3K-Akt signaling pathway;>>Focal adhesion;>>ECM-receptor interaction;>>Cell adhesion molecules;>>Regulation of actin cytoskeleton;>>Human papillomavirus infection;>>Hypertrophic cardiomyopathy;>>Arrhythmogenic right ventricular cardiomyopathy;>>Dilated cardiomyopathy
    • Gene Name：
    • ITGB8
    • Protein Name：
    • Integrin beta-8
    • Human Gene Id：
    • 3696
    • Human Swiss Prot No：
    • P26012
    • Immunogen：
    • Synthesized peptide derived from part region of human protein
    • Specificity：
    • ITB8 Polyclonal Antibody detects endogenous levels of protein.
    • Formulation：
    • Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
    • Source：
    • Polyclonal, Rabbit,IgG
    • Dilution：
    • WB 1:500-2000 ELISA 1:5000-20000
    • Purification：
    • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    • Concentration：
    • 1 mg/ml
    • Storage Stability：
    • -15°C to -25°C/1 year(Do not lower than -25°C)
    • Observed Band(KD)：
    • 84kD
    • Background：
    • This gene is a member of the integrin beta chain family and encodes a single-pass type I membrane protein with a VWFA domain and four cysteine-rich repeats. This protein noncovalently binds to an alpha subunit to form a heterodimeric integrin complex. In general, integrin complexes mediate cell-cell and cell-extracellular matrix interactions and this complex plays a role in human airway epithelial proliferation. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008],
    • Function：
    • function:Integrin alpha-V/beta-8 is a receptor for fibronectin.,similarity:Belongs to the integrin beta chain family.,similarity:Contains 1 VWFA domain.,subunit:Heterodimer of an alpha and a beta subunit. Beta-8 associates with alpha-V.,tissue specificity:Placenta, kidney, brain, ovary, uterus and in several transformed cells. Transiently expressed in 293 human embryonic kidney cells.,
    • Subcellular Location：
    • Cell membrane ; Single-pass type I membrane protein .
    • Expression：
    • Placenta, kidney, brain, ovary, uterus and in several transformed cells. Transiently expressed in 293 human embryonic kidney cells.

    Attributes

    • Code：
    • YN1771
    • Size
    • 40μL / 100μL / 200μL
    • Price$：
    • 150 / 280 / 450
    • Delivery：
    • 2024-05-03
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