Txk Polyclonal Antibody
- Catalog No.:YT4790
- Applications:IHC;IF;ELISA
- Reactivity:Human;Rat;Mouse;
- Target:
- Txk
- Fields:
- >>Leukocyte transendothelial migration
- Gene Name:
- TXK
- Protein Name:
- Tyrosine-protein kinase TXK
- Human Gene Id:
- 7294
- Human Swiss Prot No:
- P42681
- Mouse Swiss Prot No:
- P42682
- Immunogen:
- Synthesized peptide derived from the Internal region of human Txk.
- Specificity:
- Txk Polyclonal Antibody detects endogenous levels of Txk protein.
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- TXK;PTK4;RLK;Tyrosine-protein kinase TXK;Protein-tyrosine kinase 4;Resting lymphocyte kinase
- Molecular Weight(Da):
- 61kD
- Background:
- catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. TEC subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 SH2 domain.,similarity:Contains 1 SH3 domain.,tissue specificity:Expressed in T-cells and some myeloid cell lines.,
- Function:
- catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. TEC subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 SH2 domain.,similarity:Contains 1 SH3 domain.,tissue specificity:Expressed in T-cells and some myeloid cell lines.,
- Subcellular Location:
- Cytoplasm . Nucleus . Cell membrane ; Peripheral membrane protein . Localizes in the vicinity of cell surface receptors in the plasma membrane after receptor stimulation. Translocates into the nucleus and enhances IFN-gamma gene transcription in T-cells.
- Expression:
- Expressed in T-cells and some myeloid cell lines. Expressed in Th1/Th0 cells with IFN-gamma-producing potential.
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- Antibody-FAQs
- Products Images
- Immunohistochemical analysis of paraffin-embedded human oophoroma. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).