EPHA3 (Phospho Tyr602) rabbit pAb

  • Catalog No.：YP1608
  • Applications：WB;ELISA
  • Reactivity：Human;Mouse;Rat
    • Target：
    • EPHA3
    • Fields：
    • >>Axon guidance
    • Gene Name：
    • EPHA3 ETK ETK1 HEK TYRO4
    • Protein Name：
    • EPHA3 (Phospho Tyr602)
    • Human Gene Id：
    • 2042
    • Human Swiss Prot No：
    • P29320
    • Mouse Swiss Prot No：
    • P29319
    • Immunogen：
    • Synthesized peptide derived from human EPHA3 (Phospho Tyr602)
    • Specificity：
    • This antibody detects endogenous levels of Human,Mouse,Rat EPHA3 (Phospho Tyr602)
    • Formulation：
    • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
    • Source：
    • Polyclonal, Rabbit,IgG
    • Dilution：
    • WB 1:1000-2000 ELISA 1:5000-20000
    • Purification：
    • The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
    • Concentration：
    • 1 mg/ml
    • Storage Stability：
    • -15°C to -25°C/1 year(Do not lower than -25°C)
    • Other Name：
    • Ephrin type-A receptor 3 (EC 2.7.10.1;EPH-like kinase 4;EK4;hEK4;HEK;Human embryo kinase;Tyrosine-protein kinase TYRO4;Tyrosine-protein kinase receptor ETK1;Eph-like tyrosine kinase 1)
    • Observed Band(KD)：
    • 130kD
    • Background：
    • This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Two alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2008],
    • Function：
    • catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,disease:Defects in EPHA3 may be a cause of colorectal cancer (CRC) [MIM:114500].,function:Receptor for members of the ephrin-A family. Binds to ephrin-A2, -A3, -A4 and -A5. Could play a role in lymphoid function.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 SAM (sterile alpha motif) domain.,similarity:Contains 2 fibronectin type-III domains.,tissue specificity:Widely expressed. Highest level in placenta.,
    • Subcellular Location：
    • [Isoform 1]: Cell membrane ; Single-pass type I membrane protein .; [Isoform 2]: Secreted .
    • Expression：
    • Widely expressed. Highest level in placenta.

    Attributes

    • Code：
    • YP1608
    • Size
    • 50μL / 100μL / 200μL
    • Price$：
    • 190 / 340 / 600
    • Delivery：
    • 2024-04-28
    Order

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