Recombinant Human CD340 protein ,C- His Tag

  • Catalog No.:YD2232
  • Reactivity:Human
    • Purity:
    • >90% as determined by SDS-PAGE
    • In Vivo:
    • < 1.0 EU per μg of the protein as determined by the LAL method.
    • Sequence:
    • A DNA sequence encoding the human ERBB2(Met1-Thr652) was fused with the C-terminal His Tag
    • Human Swiss Prot No:
    • P04626
    • Formulation:
    • Supplied as solution form in PBS pH 7.5./ Lyophilized from PBS pH 7.5.
    • Source:
    • Mammalian cells
    • Dilution:
    • Reconstitute in sterile water for a stock solution
    • Concentration:
    • >90% as determined by SDS-PAGE
    • Storage Stability:
    • Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 °C for one week . Store at -20 to -80 °C for twelve months from the date of receipt.
    • Other Name:
    • HER-2,HER-2/neu,HER2,MLN 19,MLN19,NEU,NGL,TKR1
    • Subcellular Location:
    • [Isoform 1]: Cell membrane ; Single-pass type I membrane protein. Early endosome . Cytoplasm, perinuclear region. Nucleus. Translocation to the nucleus requires endocytosis, probably endosomal sorting and is mediated by importin beta-1/KPNB1. Also detected in VPS35-positive endosome-to-TGN retrograde vesicles (PubMed:31138794). .; [Isoform 2]: Cytoplasm. Nucleus.; [Isoform 3]: Cytoplasm. Nucleus.
    • Expression:
    • Expressed in a variety of tumor tissues including primary breast tumors and tumors from small bowel, esophagus, kidney and mouth.