Catalog: YT6860
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
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Main Information
Target
FRPD2
Host Species
Rabbit
Reactivity
Human
Applications
WB
MW
144kD (Calculated)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-2000
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
This antibody detects endogenous levels of FRPD2 at Human
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Calculated)
144kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from human FRPD2 AA range: 1161-1211
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Specificity:
This antibody detects endogenous levels of FRPD2 at Human
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Gene Name:
FRMPD2 PDZD5C PDZK4 PDZK5C
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Protein Name:
FRPD2
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Background:
This gene encodes a peripheral membrane protein and is located in a region of chromosome 10q that contains a segmental duplication. This copy of the gene is full-length and is in the telomeric duplicated region. Two other more centromerically proximal copies of the gene are partial and may represent pseudogenes. This full-length gene appears to function in the establishment and maintenance of cell polarization. The protein is recruited to cell-cell junctions in an E-cadherin-dependent manner, and is selectively localized at the basolateral membrane in polarized epithelial cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2009],
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Function:
Caution:Could be the product of a pseudogene. This is the product of related genes or pseudogenes located in a region of chromosome 10q which contains a segmental duplication resulting in three nearly identical regions.,similarity:Contains 1 FERM domain.,similarity:Contains 1 KIND domain.,similarity:Contains 1 PDZ (DHR) domain.,similarity:Contains 2 PDZ (DHR) domains.,similarity:Contains 3 PDZ (DHR) domains.,
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Cellular Localization:
Cytoplasm . Basolateral cell membrane . Cell junction, tight junction . Colocalizes with CTNNB1, CDH1 and PKP4 at the basolateral membrane. Colocalizes with TJP1 at tight junctions. Its recruitment to cell-cell contacts requires CDH1.
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Tissue Expression:
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Reference Citation({{totalcount}})
Catalog: YT6860
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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