Catalog: YT4569
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
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Main Information
Target
TBX2/3
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, ELISA
MW
79kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-1:2000; ELISA 1:20000; Not yet tested in other applications.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
TBX2/3 Polyclonal Antibody detects endogenous levels of TBX2/3 protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
79kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
The antiserum was produced against synthesized peptide derived from human TBX3. AA range:271-320
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Specificity:
TBX2/3 Polyclonal Antibody detects endogenous levels of TBX2/3 protein.
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Gene Name:
TBX2/TBX3
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Protein Name:
T-box transcription factor TBX2/3
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Other Name:
TBX3 ;
T-box transcription factor TBX3 ;
T-box protein 3 ;
TBX2 ;
T-box transcription factor TBX2 ;
T-box protein 2
T-box transcription factor TBX3 ;
T-box protein 3 ;
TBX2 ;
T-box transcription factor TBX2 ;
T-box protein 2
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Database Link:
Background:
This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This protein is a transcriptional repressor and is thought to play a role in the anterior/posterior axis of the tetrapod forelimb. Mutations in this gene cause ulnar-mammary syndrome, affecting limb, apocrine gland, tooth, hair, and genital development. Alternative splicing of this gene results in three transcript variants encoding different isoforms; however, the full length nature of one variant has not been determined. [provided by RefSeq, Jul 2008],
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Function:
Disease:Defects in TBX3 are the cause of ulnar-mammary syndrome (UMS) [MIM:181450]. UMS is characterized by ulnar ray defects, obesity, hypogenitalism, delayed puberty, hypoplasia of nipples and apocrine glands.,Function:Transcriptional repressor involved in developmental processes. Probably plays a role in limb pattern formation.,similarity:Contains 1 T-box DNA-binding domain.,tissue specificity:Widely expressed.,
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Cellular Localization:
Nucleus .
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Tissue Expression:
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Research Areas:
>>Signaling pathways regulating pluripotency of stem cells
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Signaling Pathway
Reference Citation({{totalcount}})
Catalog: YT4569
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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